Mass spectrometer is an instrument that produces ions and separates them according to mass to charge (m/z) ration. The components of a mass spectrometer include ion source, mass analyzer, detector, and vacuum system. Various mass spectrometers have been developed to meet different challenging requirements. Next, we will introduce some mass spectrometers to accelerate your research.
The TSQ Quantum Access MAX triple quadrupole mass spectrometer that is often equipped with liquid chromatography (LC) was introduced by Thermo Scientific. This instrument is equipped with the mass range up to m/z 3000, highly Selective Reaction Monitoring (H-SRM), quantitation-enhanced data-dependent MS/MS (QED-MS/MS), fast positive/negative mode switching, and comprehensive application-specific software. Based on these features, it can provide excellent sensitivity, specificity, and flexibility and can meet a wide range of application needs, like pharmaceutical, environmental, food safety, clinical research, and forensics.
The Thermo Scientific has introduced the Orbitrap Fusion Lumos Tribrid Mass Spectrometer for advanced proteomics, metabolomics, and biopharma. This high-performance mass spectrometer contains three mass analyzers, including quadrupole, Orbitrap, and linear ion trap (LIT). It is featured with a new API interface, advanced Quadrupole technology, high-field Orbitrap analyzer, and a dual-pressure linear ion trap for various applications, including post-translational modification (PTM) analysis, protein quantitation, intact protein analysis, and small molecule analysis.
The Agilent 6540 UHD Quadrupole Time-of-Flight Accurate-Mass Mass Spectrometer combines the quadrupole and time-of-flight technology. This instrument with Agilent Jet Stream technology, Ion Beam Compression (IBC), Enhanced Mirror Technology (EMT), and MassHunter Workstation data mining tools can deliver exceptional sensitivity, dynamic range, isotopic fidelity, mass accuracy and resolution to meet various needs.
Q Exactive hybrid quadrupole-Orbitrap mass spectrometer introduced by Thermo Scientific has high-performance quadrupole with high-resolution and accurate-mass (HR/AM) Orbitrap detection. The instrument has the advantages of high resolving power (up to 140,000), maximum scan speed (12 Hz), fast scan-to-scan polarity switching, as well as spectrum multiplexing and advanced signal processing. It can be widely used in proteomics research, metabolomics research, clinical research, and forensic toxicology.
Like Q Exactive mass spectrometer, the Q Exactive Plus Hybrid Quadrupole Orbitrap Mass Spectrometer combine the quadrupole and HR/AM Orbitrap technologies to accelerate a wide range of applications. For Q Exactive Plus mass spectrometer, there are several approaches to quantitation including selected ion monitoring (SIM), parallel reaction monitoring (PRM), and data-independent acquisition (DIA). In addition, advanced axial beam guide (AABG) and advanced quadrupole technology (AQT) are helpful for greater sensitivity as well as maximum robustness and superior precursor isolation.
With years of development, Creative Proteomics can provide the reliable services to meet a variety of needs by these instruments. If you want to know more detailed information, please feel free to contact us.