Histopathology Services

Comprehensive Histopathology Solutions

Creative Proteomics offers cutting-edge histopathology services designed to meet the diverse needs of the life sciences sector. From sample processing, staining, and method development to digital pathology and image analysis, we provide a comprehensive, one-stop service that addresses the requirements of every stage of pathological research. You are free to select from a variety of testing panels to suit your specific needs. Furthermore, our team of expert scientists can develop customized solutions tailored to various tissue types and disease models.

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Submit Your Request Now

What we provide
Panels
Workflow
Quality control
Why choose

Our Core Capabilities

We offer a flexible, full-service histology platform designed to support the diverse needs of the healthcare and life sciences communities.

Histology & Tissue Processing

Our wet lab is equipped to handle a wide variety of specimen types with precision and consistency.

Routine & Complex Processing: Expertise in biopsy handling, large resections, and specialized decalcification protocols.
Multi-Species Expertise: Proficient in processing human clinical samples as well as animal models (xenografts, GEMM, toxicology models).
Custom Embedding: Precise orientation for optimal tissue cross-sections.

Advanced Staining & Biomarkers

Beyond standard H&E, we utilize a vast library of stains and antibodies to reveal the molecular and architectural details of tissue.

Immunohistochemistry (IHC): Automated platforms for high-throughput, reproducible staining of diagnostic and predictive markers.
Special Stains: Histochemical stains for microorganisms, fibrosis, pigments, and cellular components.
Assay Development: Custom optimization of novel antibodies for investigational studies and validation.

Digital Pathology & Image Analysis

We leverage cutting-edge scanning technology to digitize physical glass slides into high-resolution whole-slide images (WSI).

Remote Collaboration: Instant sharing of cases for second opinions or multi-site research reviews.
Quantitative Analytics: AI-assisted tools for unbiased cell counting, tumor scoring, and morphometric analysis.
Secure Archiving: Permanent digital storage of pathology assets.

Consultation & Pathology Review

Our pathology team provides intellectual leadership alongside technical services.

Diagnostic Reporting: Clear, actionable reports for clinical management.
Study Design: Consulting on tissue collection protocols, fixation methods, and scoring systems prior to project launch.

Histopathology solution at Creative Proteomics

Technical Menu: Staining & Biomarkers

We offer an extensive menu of histochemical and immunohistochemical stains tailored to various tissue types and disease states. While H&E is the standard for morphology, our advanced staining capabilities allow for the specific characterization of proteins and pathogens.

Routine & Special Stains

Beyond standard Hematoxylin & Eosin (H&E), our special stains library aids in the identification of pathogens, connective tissue pathologies, and mineral deposition.

Connective Tissue: Masson's Trichrome (Fibrosis), Reticulin (Architecture), Elastin.
Microorganisms: GMS (Fungi), PAS/PAS-D (Fungi/Glycogen), Gram Stain (Bacteria), AFB (Mycobacteria).
Pigments & Minerals: Prussian Blue (Iron), Von Kossa (Calcium), Congo Red (Amyloid).

Immunohistochemistry (IHC) Panels

Our automated staining platforms ensure consistent intensity and background clarity for critical biomarkers, essential for both diagnostic sub-typing and research quantification.

Oncology Screen: Ki-67 (Proliferation), p53, Cytokeratins (AE1/AE3, CK7, CK20), Vimentin.
Breast Panel: ER (Estrogen Receptor), PR (Progesterone Receptor), HER2, Mammaglobin.
Immune Profiling (R&D): CD3, CD4, CD8, CD20 (B-cells), CD68 (Macrophages), PD-L1.
Custom Antibody Validation: For corporate partners, we offer optimization services to validate novel antibodies on control tissues prior to study deployment.

Workflow

workflow of our histopathology service

Quality Management

We maintain a rigorous quality management system to ensure data integrity.

Standardized Procedures

All histopathology processes follow strict SOPs, ensuring consistent and reproducible results across all samples.

Stepwise Quality Control

Every stage is rigorously monitored using validated reagents, automated equipment, and double-checks by experienced pathologists.

Client Assurance

Final reports include method details and quality checks, with prompt communication for any deviations or special considerations.

Why Choose Creative Proteomics?

We combine medical rigor with scientific flexibility to deliver results you can trust.

Pathologist-Led: Our facility is directed by board-certified pathologists who oversee quality control and provide expert consultation on complex cases.
Digital Innovation: We utilize advanced Whole Slide Imaging (WSI) and AI analytics to provide high-resolution digital deliverables and quantitative insights.
Tailored Workflows: Unlike rigid high-volume labs, we adapt our processing and reporting protocols to meet your specific project or practice requirements.
Rapid Turnaround: Optimized logistics and streamlined operations ensure you get accurate results without the wait.
Direct Access: We prioritize communication. Partner with us to get direct access to technical directors and pathologists, not just a customer service line.

* For Research Use Only. Not for use in diagnostic procedures.

Our customer service representatives are available 24 hours a day, 7 days a week. Inquiry

From Our Clients

"I recently used their proteomics service for a project analyzing protein interactions in yeast models. The team was very responsive and helped clarify the methodology they employed, which made me feel confident in the results. The data quality was solid, with clear identification of several key proteins involved in our study. Their thorough analysis enabled me to pinpoint specific interactions that I hadn't considered before, which significantly improved the direction of my research. I appreciate their professionalism and support throughout the process."

Sarah Thompson, University of California, Berkeley

"Our lab collaborated with them on a project studying cancer biomarkers. The proteomics analysis provided was detailed and focused, specifically highlighting the differential expression of proteins between healthy and tumor samples. Their clear explanations of the data helped my team understand the biological implications. I also appreciated their willingness to revise the reports based on our feedback, ensuring that we had everything we needed for our publication. This collaborative spirit was invaluable."

Emily Rodriguez, Stanford University

"Our lab worked with them on a project studying the effects of diet on gut microbiota using proteomics. They used a label-free quantification method to analyze proteins in fecal samples before and after dietary intervention. The results showed significant changes in protein expression linked to microbial activity. This was pivotal for our hypothesis about diet-microbiota interactions. The clarity of their data presentation made it easy for our team to integrate these findings into our ongoing research."

Dr. Lisa Wong, University of Toronto

"My experience with Creative Proteomics during the mass spectrometry analysis was excellent. We sent in human saliva and mouse brain tissue samples, which they expertly analyzed using both LC-MS and GC-MS techniques. The results were invaluable, revealing key metabolites in the saliva and identifying biomarkers linked to brain function in the brain tissue."

Dr. Emily Carter, Senior Research Scientist

"The overall service from Creative Proteomics was outstanding. They made the entire process seamless and efficient, allowing us to focus on our research. We worked with leaf and root samples from various Arabidopsis genotypes for targeted metabolomics analysis. Their thorough profiling of primary and secondary metabolites gave us important insights into how the plants respond metabolically to environmental stress."

Dr. Laura Henderson, Plant Physiologist

"We had a pleasant collaboration with Creative Proteomics on mass spectrometry analysis of lipids. They conducted a detailed analysis of lipid species, providing us with important insights into lipid metabolism and its relationship with metabolic syndrome disease states."

Dr. Sarah Mitchell, Research Scientist

Online Inquiry

Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to for inquiries.

Great Minds Choose Creative Proteomics