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Coenzyme I Analysis Service

Coenzyme I Analysis Service

High Performance Liquid Chromatography (HPLC) is a method able to separate non-volatile, thermally unstable, and polar components separate or in a mixture. Fundamentally, chromatography is a technique used to separate the components contained in a sample. HPLC is a type of chromatography that, because of its wide application range and quantitative accuracy, is regarded as an indispensable analytical technique, particularly in the field of organic chemistry. It is also widely used as a preparation technique for the isolation and purification of target components contained in mixtures. The Russian-Polish botanist M. Tswett is generally recognized as the first person to establish the principles of chromatography. In a paper he presented in 1906, Tswett described how he filled a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of chlorophyll to flow through the chalk, separated the chlorophyll into layers of different colors. He called this technique “chromatography”. HPLC utilized the quality and quantity of both small molecules and polymeric species. High Performance Liquid Chromatography (HPLC) Analysis Services at Creative-Proteomics offers you a state-of-the-art liquid separations platform that includes standard HPLC with frequently used separation mechanisms.

Coenzyme I is also known as Nicotinamide adenine dinucleotide, which is composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Coenzyme I is found widely in all living cells. There are two forms of Coenzyme I in cells, the one is an oxidizing agent, named as NAD+ , the other is the reduced from named as NADH, which can be used as a reducing agent to donate electrons. Coenzyme I serves as an electron carrier in numerous enzymatic reactions. Coenzyme I is also used in other cellular processes, the most famous one is being a substrate of enzymes that add or remove chemical groups from proteins in the protein posttranslational modifications. The enzymes involved in NAD metabolism are targets for drug discovery due to the importance of these functions.

Coenzyme I Analysis Service at Creative Proteomics supports your research in Coenzyme I Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.

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