Niacin (Nicotinic Acid, as know as Vitamin B3) Analysis Service


Niacin (Nicotinic Acid, as know as Vitamin B3) Analysis Service

Niacin, also known as vitamin B3 and nicotinic acid, was  first described by Hugo Weidel in nicotine research in 1873. Niacin is an organic compound with the  formula C6H5NO2. Niacin is one of  the 13 kinds of human essential vitamins and belong to the vitamin B family. Niacin can be converted to  nicotinamide, which is the precursor of the coenzymes nicotinamide adenine  dinucleotide (NAD) andnicotinamide adenine dinucleotide phosphate (NADP) in  vivo and is involved in lipid metabolism, tissue respiration of the oxidation  process and carbohydrate anaerobic decomposition process.

Scientists at Creative Proteomics utilize a highly quantitative method with  high-performance liquid chromatography (HPLC)  for the determination of Niacin (Nicotinic Acid, as know as Vitamin B3) levels  in various samples, including Various Sample Type. High-Performance Liquid  Chromatography (HPLC) with UV  detection is used for the determination of Niacin (Nicotinic Acid, as know as  Vitamin B3) (OD 261 nm) levels in a lot of biological samples. This Methodology  provides accurate, reliable, and reproducible results of Niacin measurement,  which enables us to analyze of Niacin levels in vitro and in vivo Pharmaceutical and supplemental Niacin are primarily used to treat hypercholesterolemia (high  cholesterol) and pellagra (Niacin deficiency). Niacin deficiency in  the diet can cause nausea, skin and mouth lesions, anemia, headaches, and  tiredness. Insufficient Niacin may  also be observed in pandemic deficiency disease, which is caused by a lack of  five important vitamins (Niacin,  vitamin C, thiamin, vitamin D, and vitamin A) and is usually found in regions  of widespread poverty and malnutrition. The liver can synthesize Niacin from the essential amino acid  tryptophan, which is an essential amino acid found in most forms of protein. Niacin is also found in variety of  foods, including liver, chicken, beef, fish, cereal, peanuts, and legumes.

The Russian-Polish botanist M. Tswett is  generally recognized as the first person to establish the principles of  chromatography. In a paper he presented in 1906, Tswett described how he filled  a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of  chlorophyll to flow through the chalk, separated the chlorophyll into layers of  different colors. He called this technique “chromatography”. Fundamentally,  chromatography is a technique used to separate the components contained in a  sample. High Performance Liquid  Chromatography (HPLC) is a method able to separate non-volatile, thermally  unstable, and polar components separate or in a mixture. HPLC is a type of chromatography that, because of its wide  application range and quantitative accuracy, is regarded as an indispensable  analytical technique, particularly in the field of organic chemistry. It is  also widely used as a preparation technique for the isolation and purification  of target components contained in mixtures.

Niacin (Nicotinic Acid, as  know as Vitamin B3) Analysis Service at Creative Proteomics supports your research in Niacin (Nicotinic  Acid, as know as Vitamin B3) Analysis. HPLC Based Analysis Service  Platform enable us at Creative  Proteomics offers you a state-of-the-art Analysis Service.

Sample Type
Various  Sample Type

Method
High-Performance Liquid  Chromatography (HPLC) with UV  detection is used for the determination of Niacin (Nicotinic Acid, as know as Vitamin B3) (OD 261 nm) levels in a lot of  biological samples. This Methodology provides accurate, reliable, and  reproducible results of Niacin measurement, which enables us to analyze of Niacin levels in vitro and in vivo.

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