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Home > Application > Analysis Services > Niacin (Nicotinic Acid, as know as Vitamin B3) Analysis Service

Niacin (Nicotinic Acid, as know as Vitamin B3) Analysis Service

Niacin (Nicotinic Acid, as know as Vitamin B3) Analysis Service

Niacin, also known as vitamin B3 and nicotinic acid, was first described by Hugo Weidel in nicotine research in 1873. Niacin is an organic compound with the formula C6H5NO2. Niacin is one of the 13 kinds of human essential vitamins and belong to the vitamin B family. Niacin can be converted to nicotinamide, which is the precursor of the coenzymes nicotinamide adenine dinucleotide (NAD) andnicotinamide adenine dinucleotide phosphate (NADP) in vivo and is involved in lipid metabolism, tissue respiration of the oxidation process and carbohydrate anaerobic decomposition process.

Scientists at Creative Proteomics utilize a highly quantitative method with high-performance liquid chromatography (HPLC) for the determination of Niacin (Nicotinic Acid, as know as Vitamin B3) levels in various samples, including Various Sample Type. High-Performance Liquid Chromatography (HPLC) with UV detection is used for the determination of Niacin (Nicotinic Acid, as know as Vitamin B3) (OD 261 nm) levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Niacin measurement, which enables us to analyze of Niacin levels in vitro and in vivo Pharmaceutical and supplemental Niacin are primarily used to treat hypercholesterolemia (high cholesterol) and pellagra (Niacin deficiency). Niacin deficiency in the diet can cause nausea, skin and mouth lesions, anemia, headaches, and tiredness. Insufficient Niacin may also be observed in pandemic deficiency disease, which is caused by a lack of five important vitamins (Niacin, vitamin C, thiamin, vitamin D, and vitamin A) and is usually found in regions of widespread poverty and malnutrition. The liver can synthesize Niacin from the essential amino acid tryptophan, which is an essential amino acid found in most forms of protein. Niacin is also found in variety of foods, including liver, chicken, beef, fish, cereal, peanuts, and legumes.

The Russian-Polish botanist M. Tswett is generally recognized as the first person to establish the principles of chromatography. In a paper he presented in 1906, Tswett described how he filled a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of chlorophyll to flow through the chalk, separated the chlorophyll into layers of different colors. He called this technique “chromatography”. Fundamentally, chromatography is a technique used to separate the components contained in a sample. High Performance Liquid Chromatography (HPLC) is a method able to separate non-volatile, thermally unstable, and polar components separate or in a mixture. HPLC is a type of chromatography that, because of its wide application range and quantitative accuracy, is regarded as an indispensable analytical technique, particularly in the field of organic chemistry. It is also widely used as a preparation technique for the isolation and purification of target components contained in mixtures.

Niacin (Nicotinic Acid, as know as Vitamin B3) Analysis Service at Creative Proteomics supports your research in Niacin (Nicotinic Acid, as know as Vitamin B3) Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.

Sample Type
Various Sample Type

Method
High-Performance Liquid Chromatography (HPLC) with UV detection is used for the determination of Niacin (Nicotinic Acid, as know as Vitamin B3) (OD 261 nm) levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Niacin measurement, which enables us to analyze of Niacin levels in vitro and in vivo.

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