What Is CoQ10
Coenzyme Q10, also known as ubiquinone, ubidecarenone, coenzyme Q, and is abbreviated to CoQ10. It is a 1,4-benzoquinone, where Q refers to the quinone chemical group and 10 refers to the number of isoprenyl chemical subunits in its tail. CoQ10 is a coenzyme which is ubiquitous in the bodies of most animals, especially on the membranes of many organelles.
Coenzyme Q10 (CoQ10) exists in two isomeric forms: Reduced Coenzyme Q10 (CoQ10H2) and Oxidized Coenzyme Q10 (CoQ10). These isomers exhibit mirror-image three-dimensional structures. CoQ10H2 functions as a potent free radical scavenger, effectively inhibiting lipid and protein peroxidation reactions, ultimately resulting in the formation of Oxidized Coenzyme Q10 (CoQ10).
Oxidized Coenzyme Q10 (CoQ10) is a lipid-soluble compound with widespread presence in biological organisms. It primarily resides on the inner mitochondrial membrane, where it actively participates in crucial processes like electron transport within the respiratory chain, antioxidation, and metabolic regulation. It serves as a natural antioxidant and proficiently eliminates free radicals. In clinical practice, Coenzyme Q10 is frequently employed for adjunctive therapy in various conditions, including hypertension, chronic heart failure, ischemic cardiomyopathy, hepatitis, and cancer.
Conversely, Reduced Coenzyme Q10 (CoQ10H2) acts as an activator of cellular metabolism and functions as an immunostimulant. It possesses remarkable antioxidant properties and demonstrates the capacity to eliminate free radicals. In clinical settings, CoQ10H2 finds extensive application in the treatment of cardiovascular diseases, neurological disorders, hypertension, hyperlipidemia, diabetes, severe hepatitis, and various other medical conditions.
CoQ10 is well defined as a crucial component of the electron transport chain and participates in aerobic cellular respiration in mitochondria which converts biochemical energy from nutrients into adenosine triphosphate (ATP) and about ninety-five percent of the human body's energy is generated this way. CoQ10 functions as an electron carrier from enzyme complex I and enzyme complex II to complex III in aerobic cellular respiration. This is very important in the process, since no other molecule can perform this function. Thus, the primary function of CoQ10 in every cell of the body is in generating energy. CoQ10 continuously goes through an oxidation–reduction cycle as an energy carrier and it becomes reduced when it accepts electrons, as it gives up electrons, it becomes oxidized. CoQ10 can act as an antioxidant because the CoQ10 molecule can give up one or both electrons quite easily in its reduced form.
Coenzyme Q10 Analysis Service
Coenzyme Q10 Analysis Service at Creative Proteomics supports your research in Coenzyme Q10 Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.
|Coenzyme Q10, reduced
Animal and Clinical Tissue Specimens: 200 mg/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice to avoid repeated freeze-thaw cycles.
Serum and Plasma: 200 μL/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice.
Urine: 1 mL/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice.
Microbes and Cells: 1×107 cells/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice.
Fecal Samples: 200 mg/sample, flash-frozen in liquid nitrogen, stored at -80°C, and shipped with dry ice.
For other sample types, please consult our technical support or sales team.
Note: Avoid repeated freeze-thaw cycles.