Coenzyme Q10, also known as ubiquinone, ubidecarenone, coenzyme Q,  and is abbreviated to CoQ10. It is a  1,4-benzoquinone, where Q refers to the quinone chemical group and 10 refers to  the number of isoprenyl chemical subunits in its tail. CoQ10 is a coenzyme which is ubiquitous in the bodies of most  animals, especially on the membranes of many organelles.

Scientists at Creative Proteomics utilize a highly quantitative method with  high-performance liquid chromatography (HPLC)  for the determination of Coenzyme Q10 levels in various samples, including  Yeast, Tissue, Plant, and more. High-Performance Liquid Chromatography (HPLC) with UV detection is used for the  determination of CoQl0 (275 nm) levels in a lot of biological samples. This  Methodology provides accurate, reliable, and reproducible results of Coenzyme  Q10 measurement, which enables us to analyze of Coenzyme Q10 levels in vitro  and in vivo.

CoQ10 is well defined as a crucial component of the  electron transport chain and participates in aerobic cellular respiration in  mitochondria which converts biochemical energy from nutrients into adenosine  triphosphate (ATP) and about  ninety-five percent of the human body’s energy is generated this way. CoQ10 functions as an electron carrier  from enzyme complex I and enzyme complex II to complex III in aerobic cellular  respiration. This is very important in the process, since no other molecule can  perform this function. Thus, the primary function of CoQ10 in every cell of the body is in generating energy. CoQ10 continuously goes through an  oxidation–reduction cycle as an energy carrier and it becomes reduced when it  accepts electrons, as it gives up electrons, it becomes oxidized. CoQ10 can act as an antioxidant because  the CoQ10 molecule can give up one  or both electrons quite easily in its reduced form.

The Russian-Polish botanist M. Tswett is  generally recognized as the first person to establish the principles of  chromatography. In a paper he presented in 1906, Tswett described how he filled  a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of  chlorophyll to flow through the chalk, separated the chlorophyll into layers of  different colors. He called this technique “chromatography”. Fundamentally,  chromatography is a technique used to separate the components contained in a  sample. High Performance Liquid  Chromatography (HPLC) is a method able to separate non-volatile, thermally  unstable, and polar components separate or in a mixture. HPLC is a type of chromatography that, because of its wide  application range and quantitative accuracy, is regarded as an indispensable  analytical technique, particularly in the field of organic chemistry. It is  also widely used as a preparation technique for the isolation and purification  of target components contained in mixtures.

Coenzyme  Q10 Analysis Service at Creative Proteomics supports your  research in Coenzyme Q10 Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.

Sample  Type
 Yeast,  Tissue, Plant, and more

Method
 High-Performance  Liquid Chromatography (HPLC) with UV  detection is used for the determination of CoQl0 (275 nm) levels in a lot of biological samples. This Methodology provides  accurate, reliable, and reproducible results of Coenzyme Q10 measurement, which enables us to analyze of Coenzyme Q10 levels in vitro and in  vivo.

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