Antibiotic, is a class of secondary metabolites produced by microorganisms (including bacteria, fungi, and actinomycetes) or higher plants and animals in the course of their lives that have anti-pathogenic or other activities and can interfere with the developmental functions of other living cells chemical substances. Clinically used antibiotics are extracts from microbial cultures and chemically synthesized or semi-synthesized compounds. The antibacterial or bactericidal effect of antibiotics and other antimicrobial agents is mainly aimed at killing the mechanism that "bacteria have and humans (or other plants and animals) do not have", which consists of four major mechanisms of action, namely: inhibition of bacterial cell wall synthesis, enhancement of bacterial cell membrane permeability, interference with bacterial protein synthesis, and inhibition of bacterial nucleic acid replication and transcription.
Antibiotic Targeted Metabolomics Workflow
Substance List
Sulfonamides: 30 species
Quinolones: 20 species
Tetracyclines: 6 species
Macrolides:16 species
β-lactams:14 species
Other 3 species
Technical Advantages
1. High throughput: qualitative and quantitative analysis of multiple antibiotics at one time.
2. Accurate quantification and good reproducibility.
3. High sensitivity and low detection limit.
4. Strict quality control system.
5. Good service system.
Antibiotic Targeted Metabolomics Application
Drug Discovery
Drug Efficacy Studies
Drug Toxicology Evaluation
Antibiotic Detection In Food