Succinic acid, is also known as Butanedioic Acid and it is a dicarboxylic acid of molecular formulation C4H6O4 which is widely distributed in almost all plant and animal tissues. Succinic acid plays a important role in intermediary metabolism. Succinic acid is a colourless crystalline solid, soluble in water and it ionizesto anions, that is conjugates to a conjugate base in an aqueous solution, called succinate, which plays a role in the citric acid cycle, an energy-yielding process in all living organisms.
Scientists at Creative Proteomics utilize a highly quantitative method with high-performance liquid chromatography (HPLC) for the determination of Succinic Acid levels in various samples, including Food, Beverage and more. High-Performance Liquid Chromatography (HPLC) using a differential refractive index detector (RID) for the determination of Succinic acid levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Succinic acid measurement, which enables us to analyze of Succinic acid levels in vitro and in vivo.
Succinate acid is an intermediate in the citric acid cycle, which is is a series of chemical reactions used by all aerobic organisms to generate energy in the form of guanosine triphosphate through the oxidation of acetyl-CoA derived from carbohydrates, fats and proteins . Succinate acid serves as an electron donor to the electron transport chain,which is a series of compounds that transfer electrons from electron donors to electron acceptors viaredox reactions. The conversion of succinate acid to fumarate is catalysed by the enzyme succinate dehydrogenase , which is a 4 subunit membrane-bound lipoprotein and can couple the oxidation of succinate to the reduction of ubiquinone. Succinic acid was first obtained as a distillation product of amber and the common Method of synthesis of Succinic acid is the catalytic hydrogenation of maleic acid or its anhydride, although other Methods are being used and tested. Succinic acid has uses in certain drug compounds, in agricultural, food production, and in manufacturing.
The Russian-Polish botanist M. Tswett is generally recognized as the first person to establish the principles of chromatography. In a paper he presented in 1906, Tswett described how he filled a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of chlorophyll to flow through the chalk, separated the chlorophyll into layers of different colors. He called this technique “chromatography”. Fundamentally, chromatography is a technique used to separate the components contained in a sample. High Performance Liquid Chromatography (HPLC) is a method able to separate non-volatile, thermally unstable, and polar components separate or in a mixture. HPLC is a type of chromatography that, because of its wide application range and quantitative accuracy, is regarded as an indispensable analytical technique, particularly in the field of organic chemistry. It is also widely used as a preparation technique for the isolation and purification of target components contained in mixtures.
Succinic acid Analysis Service at Creative Proteomics supports your research in Succinic acid Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.
Food, Beverage and more
High-Performance Liquid Chromatography (HPLC) using a differential refractive index detector (RID) for the determination of Succinic acid levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Succinic acid measurement, which enables us to analyze of Succinic acid levels in vitro and in vivo.
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