Valeric acid is also known as pentanoic acid. It is a straight-chain alkyl carboxylic acid. Its chemical formula is C5H10O2. Valeric acid has a very unpleasant odor like the carboxylic acids with low molecular weight. It can be found in the perennial flowering plant valerian naturally, which is also known as valeriana officinalis. The most important function of valeric acid is in the synthesis of its esters. Volatile esters synthesized from valeric acid have more pleasant odors compared with valeric acid. It is can be used in perfumes and cosmetics.
Scientists at Creative Proteomics utilize a highly quantitative method with high-performance liquid chromatography (HPLC) for the determination of Valeric acid levels in various samples, including Tissue, Plant, Bacterial, Cells and more. High-Performance Liquid Chromatography (HPLC) using a differential refractive index detector (RID) for the determination of Valeric acid levels in a lot of biological samples.
Pentyl valerate and ethyl valerate derived from valeric acid have fruity flavors and are used as food additives usually. Valeric acid has similar chemical structure with gamma-Hydroxybutyric acid, which is a naturally occurring neurotransmitter and a psychoactive drug. Valeric acid also has similar structure with neurotransmitter gamma-Aminobutyric acid, which is the chief inhibitory neurotransmitter in the mammalian central nervous system. Valeric acid lacks the alcohol and amine functional groups, which contribute to the biological activities of GHB and GABA. Valeric acid is methylated and results in the formation of mevalonic acid. Irritation can be accused by valeric acid when it contacts with the skin, mucous membranes or eyes. Valproic acid, which is abbreviated as VPA, is a branched short-chain fatty acid derived from valeric acid naturally occurring. Valproic acid can be used in the treatment of seizures and epilepsy rather than anxiety and psychiatric disorders. Recent work has shown that valproic acid can be served as an adjuvant agent in the treatment of HIV infection, cancer and neurodegenerative disease due to the inhibitory action to the histone deacetylase. Due to the multiple mechanisms of action and acceptable safety profile of valproic acid, it can be used in pediatric epilepsy widely.
Tissue, Plant, Bacterial, Cells and more
High-Performance Liquid Chromatography (HPLC) using a differential refractive index detector (RID) for the determination of Valeric acid levels in a lot of biological samples, Tissue, Plant, Bacterial, Cells and more. This Methodology provides accurate, reliable, and reproducible results of Valeric acid measurement, which enables us to analyze of Valeric acid levels in vitro and in vivo.
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