Salvianolic Acid B is an organic chemical compound with the molecular formula is C36H30O16. Salvianolic Acid B is isolated from the roots and rhizomes of Labiatae plant Salvia Salvia miltiorrhiza bge. Salvianolic Acid B is brown and yellow dry powder. The pure Salvianolic Acid B is white powder and tastes a litter bitter. Salvianolic Acid B is soluble in water.
Scientists at Creative Proteomics utilize a highly quantitative method with high-performance liquid chromatography (HPLC) for the determination of Salvianolic Acid B levels in various samples, including Plant Tissue and more. High-Performance Liquid Chromatography (HPLC) with UV detection is used for the determination of Salvianolic Acid B (286 nm) levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Salvianolic Acid B measurement, which enables us to analyze of Salvianolic Acid B levels in vitro and in vivo.
Salvianolic Acid B has important pharmacological effects on the heart, brain, liver, kidney and other organs. Salvianolic Acid B is a cell protective antioxidant, which can protect the cells from the damage of the ROS. Salvianolic Acid B is also involved in the ischemic heart disorders and Alzheimer′s disease. Salvianolic Acid B is proposed that can inhibit the EGFR, PDGF and MMP-9, the TGF-β1/Smads and NF-κB signaling pathways. Salvianolic Acid B is also reported as scavengers of reactive oxygen species resulting in reducing the adherence of leukocytes to endothelial cells and then inhibits matrix metalloproteinases and inflammation. Salvianolic Acid B also can reduce the lipid peroxidation and the leakage of lactic acid dehydrogenase in damaged cardiac tissue resulting in the cardioprotective effects in the cardiac tissue.
The Russian-Polish botanist M. Tswett is generally recognized as the first person to establish the principles of chromatography. In a paper he presented in 1906, Tswett described how he filled a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of chlorophyll to flow through the chalk, separated the chlorophyll into layers of different colors. He called this technique “chromatography”. Fundamentally, chromatography is a technique used to separate the components contained in a sample. High Performance Liquid Chromatography (HPLC) is a method able to separate non-volatile, thermally unstable, and polar components separate or in a mixture. HPLC is a type of chromatography that, because of its wide application range and quantitative accuracy, is regarded as an indispensable analytical technique, particularly in the field of organic chemistry. It is also widely used as a preparation technique for the isolation and purification of target components contained in mixtures.
Salvianolic Acid B Analysis Service at Creative Proteomics supports your research in Salvianolic Acid B Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.
Sample Type
Plant Tissue and more
Method
High-Performance Liquid Chromatography (HPLC) with UV detection is used for the determination of Salvianolic Acid B (286 nm) levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Salvianolic Acid B measurement, which enables us to analyze of Salvianolic Acid B levels in vitro and in vivo.
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