Progesterone Analysis Service


Progesterone Analysis Service

Progesterone is abbreviated as P4 in general and is also known as  pregn-4-ene-3,20-dione. Progesterone is  consisted of four interconnected cyclic hydrocarbons, which is an organic  compound consisting entirely of hydrogen and carbon and contains ketone and  oxygenated functional groups, as well as two methyl branches like other  steroids. Progesterone is a kind of  hydrophobic chemical compound like all steroid hormones.

Scientists at Creative Proteomics utilize a highly quantitative method with  high-performance liquid chromatography (HPLC)  for the determination of Progesterone levels in various samples, including  Serum, Tissue and more. High-Performance Liquid Chromatography (HPLC) with UV detection is used for the  determination of Progesterone (288 nm) levels in a lot of biological samples.  This Methodology provides accurate, reliable, and reproducible results of  Progesterone measurement, which enables us to analyze of Progesterone levels in  vitro and in vivo.

Progesterone  can act as a  potent agonist of the nuclear Progesterone receptor (nPR) with an affinity of KD = 1 nM, therefore, it is the most  important progestogen in the body. Progesterone  is an endogenous steroid and  progestogen sex hormone and is involved in the emenstrual cycle, pregnancy, and  embryogenesis of humans and other species. Progesterone  belongs to a family of steroid  hormones called the progestogens, which is the most important progestogen in  the body. Progesterone  is also an important metabolic intermediate in  the production of other endogenous steroids, such as the sex hormones and the  corticosteroids. In addition, Progesterone  plays a crucial role in brain  function as a neurosteroid, which is kind of endogenous or exogenous steroids  that rapidly alter neuronal excitability through interaction with ligand-gated  ion channels and other cell surface receptors. Progesterone  is on n the WHO  Model List of Essential Medicines and is the most important medications needed  in a basic health system.

The Russian-Polish botanist M. Tswett is  generally recognized as the first person to establish the principles of  chromatography. In a paper he presented in 1906, Tswett described how he filled  a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of  chlorophyll to flow through the chalk, separated the chlorophyll into layers of  different colors. He called this technique “chromatography”. Fundamentally,  chromatography is a technique used to separate the components contained in a  sample. High Performance Liquid  Chromatography (HPLC) is a method able to separate non-volatile, thermally  unstable, and polar components separate or in a mixture. HPLC is a type of chromatography that, because of its wide  application range and quantitative accuracy, is regarded as an indispensable  analytical technique, particularly in the field of organic chemistry. It is  also widely used as a preparation technique for the isolation and purification  of target components contained in mixtures.

Progesterone  Analysis  Service at Creative Proteomics supports your research in Progesterone  Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.

Sample Type
Various  Sample Type

Method
High-Performance Liquid Chromatography (HPLC) with UV detection is used for the determination of Progesterone (288 nm) levels in a lot of biological  samples. This Methodology provides accurate, reliable, and reproducible results  of Progesterone measurement, which enables us to analyze of Progesterone levels in vitro and in vivo.

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