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Liquid Chromatography (LC) Based Analysis Services

Liquid Chromatography (LC) is a form of chromatography that allows separation of complex mixtures of both semi- and non-volatile compounds based on slight differences in solubility between chemicals. This technique is a complementary to GC but effective when the compounds of interest are not volatile or are thermally labile. Liquid Chromatography (LC) Based Analysis Services at Creative Proteomics offers you a state-of-the-art liquid separations platform that includes standard LCs with frequently used separation mechanisms.


  • Agilent Ion Trap LC-MS system: The system combined with a UV detector was able to collect MS and UV data, which facility the analysis of various components. Such as polymer additives, degradents, pharmaceutical impurities, and active pharmaceutical ingredients.
  • Custom Sercices: Development and/or validation of analytical methods specific to your sample matrix, active ingredient and desired instrumentation.

We are Capable of:

  • Analysis of Residues for Identification
  • Coatings Characterization
  • Determination of Residual Acrylamide Content
  • Impurity Identification
  • Leachables and Extractables Analysis
  • Surfactant Analysis
  • Polymer Additive Analysis and Quantitation
  • Protein and Amino Acid Characterization
  • Residual Monomer and Oligomer Detection
  • Method Development and Validation

Detection Techniques:

  • Liquid Chromatography (LC)
  • Liquid Chromatography Mass Spectroscopy (LC-MS)
  • Tandem LC Mass Spectroscopy (LC/MS/MS)
  • Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry (LC-MRM)
  • Liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS)
  • Triple Quadrupole Liquid Chromatography Mass Spectrometry
  • Ion trap LC/MS/MS
  • Nano electrospray liquid chromatography tandem mass spectrometry (Nano-ESI-LC-MS-MS)
  • 2D-nano-LC-ESI LTQ-Orbitrap MS/MS

Creative Proteomics's analytical scientists are highly experienced and knowledgeable in the application of LC-MS analyses to a wide variety of industries ranging from Food & Beverage to Pharmaceuticals and much more. Experience, fast turnaround, clear concise written reports, and custom service are provided to help customers resolve your analytical and technical challenges.

* For Research Use Only. Not for use in diagnostic procedures.
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