Quinic acid is a kind of cyclitol, a cyclic polyol, and a cyclohexanecarboxylic acid and is soluble in water and crystallizes in large colorless prisms. Quinic acid is also known as a crystalline acid obtained from cinchona bark, coffee beans, and other plant products and made synthetically by hydrolysis of chlorogenic acid. The chemical compound was isolated by Nicolas Vauquelin, which is a French pharmacist in 1806 for the first time. The further chemical reactions to synthesize other compounds by using this acid as substance were investigated by German chemist Eduard Lautemann in 1863. Quinic acid can be found in the bark of Eucalyptus globulus.
Scientists at Creative Proteomics utilize a highly quantitative method with high-performance liquid chromatography (HPLC) for the determination of Quinic Acid levels in various samples, including Plant and more. High-Performance Liquid Chromatography (HPLC) using a differential refractive index detector (RID) for the determination of Quinic acid levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Quinic acid measurement, which enables us to analyze of Quinic acid levels in vitro and in vivo.
The common industrial application of Quinic acid is used as an astringent. Quinic acid is a versatile chiral starting material to synthesize many new pharmaceutical drugs. For example, Tamiflu, which is a medication for the treatment of influenza A and B strains is synthesized with Quinic acid as raw material and has been successfully developed and launched into the market. Quinic acid is also reported can be used to displace the muopioid receptor antagonist Naltrexone, even though Quinic acid was originally thought to be pharmacologically inactive.
The Russian-Polish botanist M. Tswett is generally recognized as the first person to establish the principles of chromatography. In a paper he presented in 1906, Tswett described how he filled a glass tube with chalk powder (CaCO3) and, by allowing an ether solution of chlorophyll to flow through the chalk, separated the chlorophyll into layers of different colors. He called this technique “chromatography”. Fundamentally, chromatography is a technique used to separate the components contained in a sample. High Performance Liquid Chromatography (HPLC) is a method able to separate non-volatile, thermally unstable, and polar components separate or in a mixture. HPLC is a type of chromatography that, because of its wide application range and quantitative accuracy, is regarded as an indispensable analytical technique, particularly in the field of organic chemistry. It is also widely used as a preparation technique for the isolation and purification of target components contained in mixtures.
Quinic acid Analysis Service at Creative Proteomics supports your research in Quinic acid Analysis. HPLC Based Analysis Service Platform enable us at Creative Proteomics offers you a state-of-the-art Analysis Service.
Plant and more
High-Performance Liquid Chromatography (HPLC) using a differential refractive index detector (RID) for the determination of Quinic acid levels in a lot of biological samples. This Methodology provides accurate, reliable, and reproducible results of Quinic acid measurement, which enables us to analyze of Quinic acid levels in vitro and in vivo.
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