Hexosylceramide


Sphingolipids are fundamental structural components of cell membranes. They also incorporate other components to form membrane lipid rafts. Sphingolipids are involved in the regulation of biological processes including cell growth, differentiation and apoptosis. Ceramide is the central hub of sphingolipids pathway, which includes sphingomyelins, gluco- and galactosylceramides, grouped as hexosylceramides (HexCer), lactosylceramides (LacCer), sphingosine(Sph), dihydrosphingosine (DhSph) and dihydroceramides (DhCer) among other compounds.

Hexosylceramide Analysis Service    Figure 1. N-hexadecanoyl hexosylceramide

The level of HexCer changes at different physiological, pathological and disease conditions. It has been shown that hexosylceramide levels changes in brain aging. Moreover, it has been suggested that hexosylceramide-derived sphingolipids increased in the CSF of patients with multiple sclerosis. Recently, plasma hexosylceramide were also found to be significantly regulated in chronic hepatitis C, which make them good biomarkers for the disease.

The advantages of LC-MS/MS method include relatively higher sensitivity and selectivity and short run times. With experienced scientists at Creative Proteomics, we have developed a reliable and reproducible method using highly sensitive LC-MS/MS method for the rapid identification and quantification of hexosylceramide in different sample types, which can satisfy the needs of academic and industrial study in your lab.

Feature and Advantage of Hexosylceramide Service

Sample Requirement

Metabolites Quantified in This Service

How to place an order:

ow To Place your Order


INQUIRY
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Inquiry

Online Inquiry

Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to for inquiries.

Stay in contact

  • 45-1 Ramsey Road, Shirley, NY 11967, USA
  • Tel: 1-631-275-3058
  • Fax: 1-631-614-7828
  • Email:
© 2008-2019 Creative Proteomics. All rights reserved.