Online Inquiry

Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to info@creative-proteomics.com for inquiries.
*
*
*
Please input "proteomics" as verification code.
Related Services
Home > Services > Metabolomics Service > Targeted Metabolomics > Hexosylceramide Analysis Service

Hexosylceramide Analysis Service

Sphingolipids are fundamental structural components of cell membranes. They also incorporate other components to form membrane lipid rafts. Sphingolipids are involved in the regulation of biological processes including cell growth, differentiation and apoptosis. Ceramide is the central hub of sphingolipids pathway, which includes sphingomyelins, gluco- and galactosylceramides, grouped as hexosylceramides (HexCer), lactosylceramides (LacCer), sphingosine(Sph), dihydrosphingosine (DhSph) and dihydroceramides (DhCer) among other compounds.

Hexosylceramide Analysis Service    Figure 1. N-hexadecanoyl hexosylceramide

The level of HexCer changes at different physiological, pathological and disease conditions. It has been shown that hexosylceramide levels changes in brain aging. Moreover, it has been suggested that hexosylceramide-derived sphingolipids increased in the CSF of patients with multiple sclerosis. Recently, plasma hexosylceramide were also found to be significantly regulated in chronic hepatitis C, which make them good biomarkers for the disease.

The advantages of LC-MS/MS method include relatively higher sensitivity and selectivity and short run times. With experienced scientists at Creative Proteomics, we have developed a reliable and reproducible method using highly sensitive LC-MS/MS method for the rapid identification and quantification of hexosylceramide in different sample types, which can satisfy the needs of academic and industrial study in your lab.

Feature and Advantage of Hexosylceramide Service

  • • Cutting-edge facilities
  • • Reliable & Reproducible

Sample Requirement

  • • Normal Volume: 200ul plasma; 100mg tissue; 2e7 cells
  • • Minimal Volume: 50uL plasma; 50mg tissue; 5e6 cells

Metabolites Quantified in This Service

Metabolites Detected in This Service
1HexCer-Sph
2HexCer-C12
3HexCer-C14
4HexCer-C16
5HexCer-C18
6HexCer-C18:1
7HexCer-C20
8HexCer-C22
9HexCer-C24
10HexCer-C24:1

How to place an order:

ow To Place your Order


Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us INQUIRY