Summary
Today we are going to discuss the Co-immunoprecipitation, which we always use to enrich low-abundance protein, including detecting interaction of two target proteins in vivo, defining a new partner of particular proteins and interacting protein complexes in native state. We are familiar with these applications. However, there is still something that you should know before co-immunoprecipitation experiment, such as, its theory, advantages and disadvantages.
Co-immunoprecipitation is a significant method to detect protein-protein interaction. Before this experiment, researchers should pay more attention to these aspects. So the experiment result will be ideal.
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