Welcome to Creative Proteomics, a leading provider of innovative solutions in the field of proteomics research. We are proud to offer high-quality services in peptideomics pathways annotation and enrichment analysis. Our cutting-edge technologies and expert team enable us to provide comprehensive and accurate analysis of peptide pathways, aiding in the unraveling of complex biological processes.
What is Peptideomics Pathways Annotation and Enrichment Analysis?
Peptides have important physiological functions as intrinsic signaling molecules, such as neuropeptides and peptide hormones, for cellular or interspecies communication, as toxins for capturing prey or as defense molecules against enemies and microorganisms. Peptideomics pathways annotation and enrichment analysis is a bioinformatics approach that aims to decipher the functional significance of peptides in biological pathways.
Pathways annotation involves mapping the identified peptides onto known biological pathways or networks. This process helps determine which pathways are significantly affected by the identified peptides and provides insights into their functional roles.
Enrichment analysis is used to identify over-represented pathways among the identified peptides. This analysis compares the observed number of peptides in a pathway to the expected number based on chance. Through this process, one can discern pathways profoundly influenced by the peptides, thereby indicating potential biological processes or signaling pathways that intertwine with these peptides.
Peptideomics Pathways Annotation and Enrichment Analysis by Creative Proteomics
- Peptide Identification
We employ advanced mass spectrometry-based techniques, such as liquid chromatography-tandem mass spectrometry (LC-MS/MS), to accurately identify and quantify peptides in your samples.
- Peptide sequencing
- Peptide mapping
- Peptide characterization
- Peptide quantification
- Peptide library design and synthesis
- Pathway Annotation
Our experienced bioinformatics team utilizes state-of-the-art software and databases to annotate the identified peptides with information about the corresponding pathways and biological functions.
- Pathway identification
We can analyze your peptide data and identify the pathways that are strongly associated with the peptides. This involves mapping the peptide sequences to known biological pathways and networks in databases such as KEGG, Reactome, and BioCarta.
- Pathway analysis and visualization
We can assess pathway enrichment, identify overrepresented pathways, and analyze pathway crosstalk.
- Pathway Enrichment Analysis
By comparing the observed peptide profiles to the relevant reference backgrounds, we perform enrichment analyses to identify significantly overrepresented pathways in your samples.
- Pathway annotation
- Pathway enrichment analysis
- Integration with other omics data
- Biomarker discovery
Our Technical Platform
| Content |
Instruments |
| Peptideomics Pathways Annotation |
- High Resolution Mass Spectrometer
- Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer
- SCIEX TripleTOF 6600
- Bruker timsTOF Pro
- Liquid Chromatography Mass Spectrometer (LC-MS)
- Waters Xevo TQ-S
- Agilent 6495C Triple Quadrupole LC/MS
- Gas Chromatography Mass Spectrometer (GC-MS)
- Thermo Scientific TSQ 9000
- Agilent 5977B GC/MS
|
| Pathway Enrichment Analysis |
- Liquid Chromatograph (LC)
- Thermo Scientific Ultimate 3000
- Waters Acquity UPLC
- Gas Chromatograph (GC)
- Agilent 7890B GC
- Shimadzu GC-2010 Plus
- High performance liquid chromatography-tandem mass spectrometry (LC-MS/MS)
- AB SCIEX Triple Quad 6500+
- Waters Xevo TQ-S
- Bruker impact-II
- Ion Mobility Spectrometer (IMS)
- Such as Bruker timsTOF Pro
- SCIEX TripleTOF 6600
|
Process of Peptideomics Pathways Annotation and Enrichment Analysis
- Consultation: We engage in an initial consultation to understand your research objectives and specific requirements.
- Sample preparation: We guide you through the sample preparation process, ensuring the collection and preparation of high-quality peptide samples.
- Peptide identification: Using advanced mass spectrometry techniques, we identify and quantify the peptides in your samples accurately.
- Data analysis: Our bioinformatics experts analyze the mass spectrometry data to annotate the identified peptides with pathway information.
- Pathway enrichment analysis: Statistical algorithms are applied to determine the significantly enriched pathways in your samples.
Our company aims to provide comprehensive and in-depth pathway annotation and enrichment analysis services to customers, helping them gain valuable insights into the functional roles and biological significance of identified peptides. Please contact us today and unlock the potential of peptide analysis.
* For research use only. Not for use in diagnostic procedures!
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