Welcome to Creative Proteomics, your premier partner in advancing scientific exploration through state-of-the-art single cell peptidomics analysis. We specialize in offering comprehensive solutions to elucidate the complex world of peptidomics within single cells, enabling unprecedented insight into cellular function, signaling pathways, and disease mechanisms. Our cutting-edge technologies combined with expert insights make us the leading choice for researchers navigating the frontiers of single cell peptidomics analysis.
Single Cell Peptidomics Solutions
Peptidomics, the large-scale study of endogenous peptides present in a biological system, has expanded its horizons to encompass single-cell analysis—a groundbreaking field offering a more granular and precise understanding of cellular heterogeneity. Single-cell peptidomics analysis emerges as an invaluable tool in unraveling the intricate landscape of cellular signaling events, regulatory mechanisms, and disease biomarkers at the individual cell level. By scrutinizing the peptidome within single cells, researchers gain unparalleled access to the fundamental building blocks of cellular communication and functional diversity.
Key Focus:
- Neuronal Cell Analysis
Through the comprehensive analysis of peptidomics, our distinguished scholars possess the proficiency to identify particular synaptic proteins present within neuronal cells, thereby comprehending their inherent functions and regulatory mechanisms pertaining to synaptic transmission. Furthermore, we are also capable of quantitatively examining specific peptides within neuronal cells, thereby allowing for a meticulous investigation into their pivotal roles within the complex realms of neurodevelopment and neurodegenerative diseases.
- Immune Cell Analysis
Our specialists possess the proficiency to discern and quantitatively analyze cytokines, receptors, and proteins associated with signaling pathways in immune cells. By employing the technique of single-cell peptidomics analysis, we can delve into the intricate aspects of immune cell functionality and explore the phenotypic distinctions among them.
- Cancer Cell Analysis
Through single-cell peptidomics analysis, our experts can discern protein alterations in cancer cells, such as mutations and rearrangements, among others. Furthermore, the examination of tumor antigens and their corresponding levels of expression in cancer cells permits the investigation of potential avenues for tumor immunotherapy and the evaluation of drug efficacy in combating the disease.
- Stem Cell Analysis
Through peptidomics analysis, our experts can identify specific makers and regulators in stem cells and understand their role in cell fate decisions and tissue regeneration. Through single cell peptidomics analysis, different types of stem cells and their differentiation status can be studied, as well as the application potential of stem cells in disease treatment and tissue engineering.
Our Platforms
- High-Resolution Mass Spectrometry Platforms
We employ state-of-the-art high-resolution mass spectrometers, including:
- Thermo Scientific Orbitrap Fusion Lumos Tribrid
- Bruker Daltonics maXis II ETD QTOF
- Waters SYNAPT G2-Si
- Agilent 6550 iFunnel Q-TOF LC/MS
- Shimadzu LCMS-9030 Q-TOF
- Sciex TripleTOF 6600
- JEOL AccuTOF-DART
- AB Sciex QTRAP 5500
- Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap
- Single-Cell Manipulation Platforms
Creative Proteomics harnesses cutting-edge single-cell manipulation platforms, facilitating the isolation, lysis, and analysis of individual cells with exceptional precision.
- Fluidigm C1 Single-Cell Auto Prep System
- Dolomite Single Cell RNA-Seq System
- BD Rhapsody Single-Cell Analysis System
- 10x Genomics Chromium Single Cell Controller
- WaferGen ICELL8 Single-Cell System
Our Analysis Methods
- Microfluidic Chip-Based Technologies
Our utilization of microfluidic chip-based technologies ensures efficient processing and analysis of single cell peptidomic samples, enhancing throughput and minimizing sample requirements.
- Microfluidic Systems
Employing advanced microfluidic systems, we isolate and process single cells with exceptional efficiency, minimizing sample loss and ensuring high-fidelity peptidome analysis. This technology enables unparalleled control over the cellular microenvironment and facilitates the extraction of minute peptide quantities, opening new frontiers for in-depth peptidomics investigations.
- Data Processing and Analysis
Our data analysis pipelines integrate sophisticated bioinformatics tools tailored for single cell peptidomics, facilitating the extraction of meaningful insights from complex datasets.
At Creative Proteomics, we recognize the immense potential of single cell peptidomics analysis in advancing the understanding of cell biology. Our services are geared towards equipping researchers and organizations with the tools and expertise necessary to conduct in-depth peptidomics studies, thereby enabling groundbreaking discoveries in cell science. Please contact us today and unlock the potential of peptide analysis.
* For research use only. Not for use in diagnostic procedures!
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