Creative Proteomics is a pioneering institution at the forefront of multi-omics and peptideomics analysis. Our commitment to delivering cutting-edge solutions and comprehensive insights makes us a trusted partner for researchers, pharmaceutical companies, and academic institutions worldwide. Through our advanced techniques, unparalleled expertise, and state-of-the-art instrumentation, we offer a full spectrum of services designed to unravel the complexities of biological systems. Explore how our peptideomics and multi-omics analysis can empower your research and discovery endeavors.
What is Analysis of Peptideomics and Multi-omics?
The analysis of peptideomics and multi-omics refers to the study and interpretation of data derived from complex biological systems that involve multiple levels of biological molecules, such as peptides, proteins, metabolites, genes, and other molecular entities. Peptideomics specifically focuses on the identification, quantification, and characterization of peptides in biological samples. This field utilizes mass spectrometry-based techniques to measure and analyze the presence and abundance of different peptides. Multi-omics, on the other hand, involves integrating and analyzing data from multiple omics levels, such as genomics, transcriptomics, proteomics, metabolomics, and lipidomics. The aim is to gain a comprehensive understanding of biological systems by studying the relationships and interactions between different omics layers. The analysis of peptideomics and multi-omics data requires expertise in bioinformatics, computational biology, statistics, and data integration techniques.
Analysis of Peptideomics and Multi-omics by Creative Proteomics
- Integrated Analysis of Peptideomics and Bioinformatics
- Data preprocessing
- Quality control
- Error identification and correction
- Dynamic range examination
- Integrated Analysis of Peptidomics and Lipidomics
We specialize in lipidomics analysis, where we identify and quantify various lipid classes and subclasses. Our mass spectrometry-based lipid profiling services cover phospholipids, sphingolipids, glycerolipids, and cholesterol,
- Identification of lipid-peptide interactions
- Cross-correlation analysis of peptidomics and lipidomics datasets
- Functional annotation and pathway analysis
- Integrated Analysis of Peptidomics and Transcriptomics
- Correlation analysis between peptide abundance and gene expression levels.
- Identification of peptide-gene associations and potential regulatory mechanisms.
- Generation of comprehensive datasets for deeper insights into biological processes and disease mechanisms.
- Integrated Analysis of Peptidomics and Metabolomics
We possess the capability to conduct a profound examination of the metabolites present within biological samples. This endeavor allows us to unravel the intricate web of metabolic alterations that accompany peculiar cellular phenomena or the manifestation of various disease conditions.
Our Multi-omics Analysis Approaches
| Multi-omic approach |
Molecular read-out |
Technology |
| Transcriptomics |
RNA and/or cDNA |
RT-PCR (reverse transcription-PCR) and RT-qPCR, gene arrays, RNA-sequencing |
| Proteomics |
Protein |
Liquid chromatography-mass spectrometry (LC-MS, western blotting, and ELISA |
| Metabolomics |
Metabolites |
Tandem mass spectrometry (MS/MS), nuclear magnetic resonance (NMR) spectroscopy, and HPLC |
| Genomics |
Genes (DNA) |
Sequencing, exome sequencing, data-independent acquisition (DIA) |
| Epigenomics |
Modifications of DNA |
Modification-sensitive PCR and qPCR, next-generation sequencing, mass spectrometry |
| Bioinformatics |
Multi-omic data analysis |
Machine learning, data integration, and computational modeling |
Advantages of Peptideomics and Multi-Omics Analysis
- Comprehensive Biological Insights
The integration of peptideomics and multi-omics data offers a multidimensional view of biological systems, providing unparalleled insights into cellular processes, disease mechanisms, and therapeutic targets.
- Systems-Level Understanding
By unraveling complex molecular interactions across different -omics layers, our analyses empower researchers to understand the holistic behavior of biological systems, including signaling pathways, regulatory networks, and dynamic responses to stimuli.
Our Capabilities
- Data Integration and Correlation
Integration of proteomics, genomics, transcriptomics, and metabolomics data to uncover intricate molecular relationships and regulatory networks.
- Pathway and Network Analysis
In-depth exploration of biological pathways, protein-protein interactions, and regulatory networks, providing a systems-level understanding of physiological and pathological processes.
- Multi-Omics Biomarker Discovery
Identification of robust molecular signatures and biomarkers through the integration of multi-omics data, facilitating diagnostic and prognostic advancements in various fields, including precision medicine and biomarker-driven therapy.
At Creative Proteomics, we specialize in unraveling the complexities of biological systems at the molecular level through advanced peptideomics and multi-omics analysis. By combining proteomics, genomics, transcriptomics, metabolomics, and other -omics data, our services provide a holistic view of biological processes, enabling comprehensive insights into cellular functions, disease mechanisms, and therapeutic targets. Please contact us today and unlock the potential of peptide analysis.
* For research use only. Not for use in diagnostic procedures!
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