With expertise in the field of peptide structure analysis, Creative Proteomics provides diverse peptide structure analysis services. Our services are designed to reveal peptide structures to gain a deeper understanding of their properties and functions. With our advanced technology and team of experienced scientists, we support clients across a variety of industries, including pharmaceuticals, biotechnology and academic research.
Structure of insulin-like brain secretory peptide (PDB ID: 1BOM)
Our Peptide Structure Analysis Services
Creative Proteomics has advanced circular dichroism analysis equipment capable of analyzing peptides for secondary structural features such as alpha helices, beta sheets and random coils. Deciphering the secondary structure provides insights into the peptide's stability, folding behavior, and potential functional properties.
Nuclear magnetic resonance (NMR) spectroscopy is a powerful tool for elucidating the three-dimensional structure of peptides. By analyzing chemical shifts, coupling constants, and nuclear overhauser effect (NOE) interactions, we can provide information on the spatial arrangement of atoms within the peptide. This information is critical to understanding binding interactions, conformational changes, and overall structural integrity.
Disulfide bonds play a crucial role in stabilizing the structure of peptides and proteins. With the concept of providing customers with the most professional services, Creative Proteomics leverages the power of advanced technologies such as mass spectrometry and high-performance liquid chromatography (HPLC) to continuously improve its skills in the field of disulfide bond and free cysteine residue detection to provide customers with accurate data analysis.
Creative Proteomics has extensive experience in the field of quantitative disulfide bond analysis and can help customers accurately determine the disulfide bond content in samples. With our accurate quantitative analysis, you can optimize peptide design, advance drug development and ensure quality control.
Applications of Our Peptide Structure Analysis Services
Peptide Drug Development
By analyzing peptide structures, we can help customers gain insights into the stability, folding behavior and potential modifications of peptides to optimize formulation strategies and evaluate the impact of structural changes on drug efficacy and stability.
Academic Research on Peptides
The structure of peptides is of great significance to peptide folding research, molecular interaction research, and drug design. Creative Proteomics can help customers analyze the secondary and tertiary structures of peptides and help researchers gain an in-depth understanding of the functional properties of peptides.
Peptide Characterization and Quality Control
Peptide structure analysis is critical for peptide characterization and quality control. By analyzing the secondary structure, tertiary structure, and disulfide bond information of the peptide, we can evaluate the potential modification and stability of the peptide, thereby achieving quality control of the peptide.
Highlights of Our Peptide Structure Analysis Services
- High sensitivity: Low-concentration peptide samples can also be accurately detected.
- High resolution: Different peptide components can be distinguished.
- Quantitative analysis: Disulfide bonds in polypeptides can be quantitatively analyzed.
- Wide range of applications: Suitable for various types of peptide samples, including cytokines, neurotransmitters and synthetic peptides.
- High degree of automation: Reduces human operating errors and improves the accuracy and reliability of data analysis.
Creative Proteomics offers a comprehensive suite of peptide structure analysis services. From CD-based secondary structure analysis to NMR-based three-dimensional structure determination, disulfide bond detection and quantitative analysis, we provide valuable insights into peptide structures and their functional properties. With our commitment to accuracy, reliability and scientific excellence, we are your trusted partner in uncovering peptide secrets and advancing the frontiers of biotechnology and pharmaceutical research. Contact us today to embark on a transformative journey of discovery and innovation!
Reference
- Nagata, K.; et al. Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin. J Mol Biol. 1995, 253(5):749-58.
* For research use only. Not for use in diagnostic procedures!
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