Peptidomics - Creative Proteomics
Single-Cell Mass Spectrometry of Neuropeptidomics
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Single-Cell Mass Spectrometry of Neuropeptidomics

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At Creative Proteomics, we offer cutting-edge single-cell mass spectrometry services for neuropeptidomics. Our comprehensive platform leverages advanced techniques to analyze neuropeptides at the single-cell level, providing invaluable insights into the complex landscape of neuropeptide function and regulation. With our state-of-the-art instrumentation, expertise, and a commitment to scientific excellence, we deliver precise and reliable data to meet the unique demands of neuropeptidomics research.

What is Single-Cell Mass Spectrometry?

Neuropeptidomics focuses on the comprehensive study of neuropeptides within the nervous system and their role in modulating various physiological processes. The ability to characterize neuropeptides at the single-cell level has opened up new frontiers in understanding the intricate signaling mechanisms that govern neural function. Single-cell mass spectrometry has emerged as a powerful tool for unraveling the complexity of neuropeptidomics, enabling the identification and quantification of neuropeptides with unparalleled sensitivity and specificity.

Single-Cell Mass Spectrometry Analysis by Creative Proteomics

  • Single-Cell Neuropeptidomics Profiling
    • Sample Preparation
      Optimal sample preparation is critical for single-cell neuropeptidomics.
    • Single-Cell Isolation
      We employ advanced techniques for the isolation of individual cells, enabling the precise analysis of neuropeptide content at the cellular level.
    • Neuropeptide Extraction
      Our optimized extraction methods ensure efficient recovery of neuropeptides from single cells, minimizing sample loss and maximizing detection efficiency.
  • Neuropeptide Identification and Quantification
    • High-Resolution Mass Spectrometry
      Leveraging high-resolution mass spectrometry, we accurately identify and quantify neuropeptides within individual cells, providing detailed molecular information.
    • Tandem Mass Spectrometry (MS/MS)
      Our MS/MS capabilities enable comprehensive structural characterization of neuropeptides, including sequence elucidation and post-translational modification analysis.
    • Quantitative Analysis
      We offer precise quantitative analysis of neuropeptides, facilitating comparative studies and dynamic profiling of neuropeptide expression within single cells.
  • Data Analysis and Interpretation
    • Bioinformatics and Data Mining
      Our bioinformatics tools enable in-depth analysis of neuropeptidomics data, uncovering meaningful patterns and correlations to support your research objectives.
    • Statistical Analysis
      We utilize robust statistical methods to ensure the reliable interpretation of single-cell neuropeptidomics data, facilitating confident insights and hypothesis generation.
    • Pathway Analysis
      Through pathway analysis, we provide a context-specific understanding of neuropeptide function within the broader biological landscape, shedding light on signaling cascades and regulatory networks.

Our Analysis Methods

Our single-cell neuropeptidomics services harness a suite of advanced analysis methods, combining cutting-edge instrumentation with meticulous protocols to achieve comprehensive and accurate results:

  • Nano-liquid Chromatography (nanoLC): We employ nanoLC to achieve high-resolution separation and precise elution of neuropeptides, optimizing the sensitivity and dynamic range of our analyses.
  • Single-Cell Mass Spectrometry Imaging: With the use of imaging mass spectrometry techniques, we provide spatially resolved mapping of neuropeptides within individual cells, offering a unique perspective on their localization and distribution.

Result Delivery

  • Customized Reports: We provide detailed reports summarizing the experimental methodology, results, and key findings, tailored to meet your specific research objectives.
  • Data Visualization: Our team presents neuropeptidomics data in clear and intuitive visual formats, facilitating the interpretation of complex results and the identification of meaningful trends.

Instrument Models

  • Time-of-Flight (TOF) Mass Spectrometry
  • Bruker rapifleX MALDI-TOF Mass Spectromete
  • Waters Xevo G2-XS Q-TOF Mass Spectrometer
  • Thermo Scientific Velos Pro Dual-Pressure Linear Ion Trap Mass Spectrometer
  • Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer
  • SCIEX NanoLC 425 with TripleTOF 6600 Mass Spectrometer

At Creative Proteomics, our single-cell mass spectrometry services for neuropeptidomics are designed to empower researchers and practitioners in unraveling the intricate world of neuropeptides at unprecedented resolution. Backed by a multidisciplinary team of experts and cutting-edge instrumentation, we are committed to driving scientific discoveries and fostering advancements in the field of neurobiology and neuropharmacology. Please contact us today and unlock the potential of peptide analysis.

* For research use only. Not for use in diagnostic procedures!

Our customer service representatives are available 24 hours a day, 7 days a week.

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