Creative Proteomics offers state-of-the-art integrated analysis of peptidomics and metabolomics, providing comprehensive insights into the dynamic and complex interplay between peptides and metabolites. Our cutting-edge technologies coupled with our team of expert scientists ensure accurate, reliable, and high-throughput analysis to unravel the intricate molecular mechanisms underlying various biological processes. With our integrated approach, clients gain a holistic understanding of the peptidomic and metabolomic landscapes, paving the way for breakthrough discoveries in fields such as drug development, biomarker identification, and disease research.
What is Integrated Analysis of Peptidomics and Metabolomics?
Integrated analysis of peptidomics and metabolomics entails a holistic methodology that amalgamates the exploration of peptides and metabolites to enhance our comprehension of the intricate biological processes and pathways within a particular system. Peptidomics, concerned with the identification and quantification of peptides, which are diminutive fragments of proteins, synergizes with metabolomics, which aims to identify and quantify small molecules participating in cellular processes. By amalgamating data derived from peptidomics and metabolomics, researchers can attain a more exhaustive perspective of the molecular alterations transpiring within a biological system. This integrative approach facilitates the identification of potential biomarkers, the cartography of metabolic pathways, and the illumination of biological mechanisms.
Integrated Analysis of Peptidomics and Metabolomics by Creative Proteomics
- Peptidomics Analysis
Our advanced mass spectrometry techniques allow for accurate sequencing and quantification of peptides.
- Identification and quantification of peptides from samples
- Characterization of peptide structures, modifications, and post-translational modifications
- Detection and analysis of peptide-protein interactions
- Metabolomics Analysis
We possess the capability to conduct a profound examination of the metabolites present within biological samples. This endeavor allows us to unravel the intricate web of metabolic alterations that accompany peculiar cellular phenomena or the manifestation of various disease conditions.
- Identification and quantification of metabolites from different biological matrices
- Profiling of metabolic pathways and metabolic alterations
- Metabolic fingerprinting and biomarker discovery
- Biomarker Discovery
Through the integration of peptidomics and metabolomics data, we are able to discern and validate significant biomarkers for diverse applications, encompassing disease diagnosis, monitoring treatment response, and evaluating drug toxicity.
- Pathway Analysis
We can perform pathway analysis to gain insights into the biological processes and mechanisms influenced by the identified peptides and metabolites. This analysis enables a systems-level understanding of the underlying molecular interactions and helps uncover potential therapeutic targets.
- Integration of Peptidomic and Metabolomic Data
- Comparative analysis of peptidomic and metabolomic datasets
- Correlation analysis to identify potential peptide-metabolite interactions
- Pathway analysis and network construction for comprehensive system-level insights
Results Delivery
Creative Proteomics is committed to delivering accurate, reliable, and timely results. Upon completion of the analysis, clients will receive comprehensive reports containing:
- Peptidomic and metabolomic data analysis methods and parameters used.
- Detailed identification and quantification of peptides and metabolites.
- Pathway analysis and network visualization.
- Statistical analyses and significance tests.
- Customized recommendations and interpretations from our expert scientists.
- Raw data files upon request.
Our Platform of Peptidomics and Metabolomics Integrated Analysis
- Liquid Chromatography-Mass Spectrometry (LC-MS)
- Agilent 1290 Infinity II LC System coupled with Agilent 6495 Triple Quadrupole LC/MS
- Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap Mass Spectrometer
- Gas Chromatography-Mass Spectrometry (GC-MS)
- Agilent 7890B Gas Chromatograph coupled with Agilent 5977A Mass Selective Detector
- Shimadzu GCMS-QP2010 SE Gas Chromatograph-Mass Spectrometer
- Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS):
- Bruker Autoflex Speed MALDI-TOF/TOF Mass Spectrometer
- SCIEX Triple TOF 6600 System
- Nuclear Magnetic Resonance (NMR) Spectroscopy
- Bruker AVANCE NEO 600 MHz NMR Spectrometer
- JEOL ECZS600 NMR Spectrometer
Advantages of Integrated Analysis of Peptidomics and Metabolomics
- Comprehensive Molecular Insight: By integrating peptidomic and metabolomic data, our analysis provides a comprehensive molecular picture, enabling a deeper understanding of cellular processes, disease mechanisms, and therapeutic targets.
- Metabolic Pathway Exploration: Unraveling the complex interactions between peptides and metabolites helps identify crucial metabolic pathways, enabling the discovery of novel drug targets and therapeutic strategies.
- Biomarker Discovery: Integrated analysis facilitates the identification of disease-specific peptides and metabolites as potential biomarkers for diagnostic, prognostic, and therapeutic purposes.
- Systems-level Understanding: By combining peptidomics and metabolomics, we gain a systems-level understanding of biological processes, enabling the identification of key regulatory mechanisms and potential intervention points.
Creative Proteomics provides a synergistic integration of peptidomics and metabolomics analyses, employing cutting-edge techniques and state-of-the-art instrumentation. Our services illuminate the intricate interplay between peptides and metabolites, offering a nuanced understanding of molecular dynamics, metabolic pathways, and the underlying mechanisms of diseases. If necessary, please contact us.
* For research use only. Not for use in diagnostic procedures!
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