Peptide Enrichment for Mass Spectrometry (MS)-Based Analysis
To overcome these issues of PTMs, enrichment strategies of the modified peptides of interest have been developed prior to MS analysis, such as ion exchange chromatography (IEC), immunoaffinity precipitation, and immobilized metal affinity chromatography (IMAC).
MS-Based Post-Translational Modification Analysis
MS is currently the gold standard and the most informative technique for protein analysis. Similar to conventional protein identification, MS-based methods for PTM analysis include top-down, bottom-up, and middle-down proteomics.
Protein Post-Translational Modification Quantitative Analysis
Beyond identification, we also apply MS-based approaches for the quantification of PTMs. We specialize in a wide range of PTM analyses, including phosphorylation, acetylation, glycosylation, and ubiquitination, among others.
Protein Post-Translational Modification Bioinformatics Analysis
Based on our experienced experts and popular tools , we are able to provide PTM site prediction services, such as phosphorylation site, glycosylation site, acetylation site, methylation site, SUMOylation site and ubiquitination site prediction.
