Wasp Venom Solutions
Wasp venom contains a variety of enzymes, proteins, peptides, volatile compounds and biologically active ingredients. It is a complex mixture of powerful allergens and pharmacologically active compounds, mainly composed of protein. Studies have shown that the biologically active ingredients in wasp venom have anti-cancer, antibacterial and anti-inflammatory effects. Therefore, wasp venom may be a potential and novel natural source for the development of innovative drugs and new agents for drug discovery.
Creative Proteomics provides you with solutions for wasp venom research to better understand the biochemical properties and potential applications of the wasp venom you are studying.
Omics Methods for Exploring Wasp Venom
The wasp venom contains peptides and proteins at different concentration levels, but low-abundance molecules have not been described in detail. Our proteomics and peptomics analysis based on LC-MS/MS technologies can help you change this situation, and can efficiently and accurately identify new wasp venom proteins and peptides.
- Identification of new peptides from wasp venom. The combination of HPLC and MS technology is used to identify new peptides in wasp venom. The low molecular weight peptides were separated using reversed-phase HPLC, sequenced using MS, and functionally characterized.
- Analysis of the protein composition of wasp venom. We use gel filtration chromatography, ion exchange chromatography and other methods to purify wasp toxin, mass spectrometry for sequencing, and use several bioinformatics tools and protein structure databases to model the structure.
- Transcriptome analysis of wasp venom. Transcriptome analysis provides a large amount of biological information of wasp venom, increases the number of identified toxins, allows its structural and functional characterization, and helps the complete decoding of wasp venom.
Analysis Service of Biological Characteristics of Wasp Venom
We use faster and more sensitive analysis techniques to identify the structure of wasp venom, and provide experimental services to clarify the biological characteristics of wasp venom to develop the therapeutic value of these toxins. The biological characteristics research services of wasp venom provided include but not limited to the following:
|
Biological activity |
Target molecule |
Specific performance |
| Antibacterial activity |
Wasp venom peptide/protein |
The wasp venom has antibacterial activity against gram-positive and gram-negative bacteria at very low concentrations. |
| Anti-inflammatory activity |
Wasp venom phospholipase |
Attenuate LPS-induced inflammation. |
| Genetic toxicity |
Wasp venom allergen |
Cause cell membrane rupture and genetic material changes. |
| Antitumor activity |
Wasp venom peptide |
Highly selective anti-proliferative effect. |
Applications
- Nanoparticles synthesized from nanocarriers and wasp venom peptides are used in drug delivery.
- Assess the rational design of anti-wasp venom serum.
- Develop potentially highly selective and effective antibiotics.
Advantages
Our analysis of wasp venom has the following obvious advantages, can increase the number of identified proteins/peptides, thereby helping to expand the content of the wasp venom composition you are studying, and increase the understanding of wasp venom poisoning, provide a convenient way to develop new anti-wasp venom serum and design specific immunotherapy strategies.
- Sensitive analysis technology
- Wide description of the composition of wasp venom
- In-depth study of the mechanism of action
Creative Proteomics focuses on venom research services for scientific research and treatment development purposes. The poisonous species we target include but not limited to wasps. If you are interested in the venom of any poisonous species, please contact us for specific consultation.
For research use only. Not intended for any clinical use.
