Jellyfish Venom Solutions

The venom of the almost transparent invertebrate --- jellyfish is one of the deadliest venoms in the world. It is composed of various chemicals, including peptides, enzymes, toxins, cytolysin, hemolysin, etc. Creative Proteomics provides jellyfish venom solutions to help customers identify and functionally characterize venom components.

Introduction

Jellyfish is one of the most dangerous creatures, which can significantly affect human activities and ecosystems，and its venom can cause many symptoms when poisoning humans. Jellyfish venom is composed of protein porins (cell membrane pore-forming toxins), neurotoxic peptides, biologically active lipids and other small molecules. It has a wide range of biological activities, including hemolysis, insecticidal, cardiovascular, antioxidant and cytotoxic effects. At present, the composition of jellyfish venom and its mechanism of action are far from being explored. The detailed characterization of jellyfish venom may help to understand the diversification of toxins and may become a valuable resource in drug design. Our jellyfish venom solution through proteomics can provide a platform for new protein discovery, development of practical methods for treating jellyfish biting humans and venom applications.

Our Jellyfish Venom Solutions

Research on jellyfish venom is limited by the availability of samples and the difficulty of separating pure venom. We use proteomics methods to provide jellyfish venom solutions, focusing on the identification and purification of pharmacological activities, making it a new source of drug development.

Our specific plan includes the provision of various analytical grade chemicals and reagents, sample collection and venom extraction and preparation services, as well as proteome determination and analysis services. The specific proteomics methods include but are not limited to the following methods:

Data Analysis

• Electrophoresis and image analysis. The gel image is digitized and the obtained image is analyzed using software.
• Mass spectrometry data analysis and database search. The degree of matching of the number of peptides, sequence coverage, and probability-based scores are used to identify proteins.
• Proteomic data analysis. Classify the molecular functions, biological processes, protein types and cellular components of the identified toxin molecules.

Applications

Many components in jellyfish venom may have pharmacological activity with therapeutic potential and serve as a source for future drug development. Based on our high-throughput methods to screen and characterize biologically active compounds, jellyfish venom has a bright future as a therapeutic agent.

• Anti-tumor
• Insecticide
• Antihypertensive
• Anticoagulant
• Analgesia
• Jellyfish sting treatment

Creative Proteomics helps researchers customize the solution of jellyfish venom to accelerate the subsequent application of venom. We are determined to become your first choice and trustworthy venom solution provider, according to the specific requirements and expectations of our partners, our advanced technology and experienced staff are dedicated to advancing plan to achieve partner research goals.

For more details, please feel free to contact us.

Reference

• Choudhary I, et al. Proteomic Analysis of Novel Components of Nemopilema nomurai Jellyfish Venom: Deciphering the Mode of Action. Toxins, 2019, 11(3):153.