Scorpion Venom Solutions
Scorpion venom is a highly complex mixture of peptides, enzymes, mucins, free amino acids, nucleotides, lipids, amines, heterocyclic components, inorganic salts and possibly other unknown substances. Some biologically active molecules from scorpion venom have been shown to have good pharmacological properties. These pharmacological properties of scorpion-derived biologically active molecules include antibacterial, immunosuppressive, bradykinin enhancement, analgesic and anti-cancer effects.
The diversity of scorpion venom components is a treasure among natural compounds, and these compounds may eventually enter medicines. Creative Proteomics uses advanced technology to help customers increase their understanding of scorpion venom composition, structure and function, biodiversity and genetic basis, and discover the potential applications of new molecules to promote scorpion venom research.
What Creative Proteomics Can Offer
Creative Proteomics integrates genomics, transcriptomics and proteomics methods to provide scorpion venom solutions for customers.
Discovery of Active Molecules in Scorpion Venom
Many scorpion venom components have been purified and identified. Based on the available structure and function information of these components, new venom-derived drugs can be produced, which have potential therapeutic activities for many important diseases. At present, scorpion venom components have shown activities that may be related to drug development, including antimicrobial, antimalarial, immunosuppressive and anticancer activities. We provide discovery services for molecules that may have these activities in scorpion venom, including the following researches on the active ingredients of scorpion venom.
|
Scorpion venom active ingredient |
Examples |
Applications |
| Antimicrobial peptide |
NDBP, Pandinin1, BmKbpp, Pantinin-1 |
As a scaffold to design more effective and specific antibiotics |
| Antimalarial peptide |
Scorpine, meucin-24, meucin-25 |
As a strong candidate for antimalarial treatment |
| Bradykinin enhancing peptide |
Peptide T, Peptide K12 |
As a tool to treat high blood pressure |
| Immunomodulator |
Parabutoporin, opistoporin |
As a useful biotechnological tool for the treatment of immune-mediated diseases |
| Anticancer peptide |
Chlorotoxin, margatoxin, Iberiotoxin |
As a drug candidate for the diagnosis and treatment of cancer |
Scorpion Venom Treatment
Scorpion venom can cause serious pathological effects and even death in humans. In more severe cases of poisoning, anti-venom serum can be used to neutralize the venom and reduce the morbidity and mortality of scorpion stings. We provide research services on the components of scorpion venom to help the development and treatment of anti-scorpion venom serum. The main treatment principles are:
- Scorpion venom enzyme. Treatment by neutralizing scorpion venom enzymes, such as hyaluronidase, phospholipase A2 and metalloproteinases, etc., research on these molecules can become the future direction of the development of scorpion venom treatment.
Solved Problem
- Obtain scorpion venom and toxin materials
- Characterize isolated venom components
- Discover new bioactive molecules
- Explore the pharmacological mechanism of the active ingredients of scorpion venom
The components of scorpion venom are diverse. Extensive research on these molecules can promote the development and therapeutic application of anti-venom serum from toxicology, and scorpion venom also has broad prospects in the treatment of diseases. Creative Proteomics invites you to cooperate with us to achieve your scorpion venom research goals. Please contact us to provide expertise, service and support to help you speed up discovery and innovation.
Reference
- Ortiz E, et al. Scorpion venom components as potential candidates for drug development. Toxicon, 2015, 93:125-135.
For research use only. Not intended for any clinical use.
