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Super Reaction Monitoring-SRM™ Quantitative Proteomics Services

Super Reaction Monitoring (SRM™) is a label-free next-generation proteomics technology platform established by Creative Proteomics. This platform combines Data-Dependent Analysis (DDA) and Data-Independent Acquisition (DIA) technologies to obtain data before each analysis. Shortcomings of DDA and selected reaction monitoring (SRM) in terms of depth and width that have limited researchers from examining complex biological systems are address by SRM™. The platform also allows an unmatched proteomics coverage with accurate and reproducible quantification of thousands of proteins per sample.

Tailored Solutions to Meet Your Needs

  1. For large-scale proteomics projects: This is a standardized SRM™ platform with a special database built from the DDA and the fast turnaround time. Thousands of proteins can be duplicated and precisely quantified from one sample. This option is for customers looking for reliable and rapid solutions to quantify proteome changes in their samples.
  2. For comprehensive proteomic analysis: Featuring an extended LC gradient for a deeper analysis and identification of more proteins, this option is for customers looking for an in-depth proteome quantification service.
  3. For the most extensive proteome profiling research: Equipped with the most advanced high-resolution mass spectrometer instruments and an ultra-long LC gradient, this solution maximizes the depth of the analysis and identifies the highest numbers of proteins. This is for customers looking for projects with the highest proteome coverage on the market.
  4. For rapid screening for large projects: We provide a unique solution for researchers in large studies with hundreds of samples who are looking for a reliable and fast service to quantify proteome changes on a large scale. This scheme features a shorter LC gradient which results in a faster turnaround time per sample.


Super Reaction Monitoring Workflow

Analytical Platform

AB SCIEX Triple-TOF 5600-plus, Q-Exactive, Orbitrap Fusion

Bioinformatics Analysis

Problems to be SolvedBioinformatics Analysis
Quality Assessment of ProteinDIA Data Analysis
Protein Comparison of Different SamplesMultivariate PCA Analysis
Protein Statistical AnalysisVenn Diagram
Volcano Plot
Functional AnnotationKEGG Annotation
GO Annotation
COG Annotation
Clustering AnalysisHierarchical Clustering
K-Means Clustering
Network AnalysisSTRING Analysis

Key Features

Sample Requirements

Based on our special protein extraction technology, we can quickly extract proteins from various samples and design personalized experimental schemes according to different experimental purposes. Specific requirements are as follows:

Sample TypeProteinCellAnimal TissuePlant TissueBloodUrineSerumMicrobes
Quantify100 ug1×107 cells1 g200 mg1 mL2 mL0.2-0.5 mLDry weighed: 200 mg




Learn more about SWATH and MSX-DIA.

* For Research Use Only. Not for use in the treatment or diagnosis of disease.

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Specializing in proteomics, Creative Proteomics offers cutting-edge protein analysis services. Our distinctive approach revolves around harnessing the power of DIA technology, enabling us to deliver precise and comprehensive insights that drive advancements in research and industry.

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