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Composition Analysis, which means comprehensive qualitative/quantitative analysis of specific ingredients in the submitted samples with integrated analytical techniques, is often required for synthesis & manufacture of fine chemicals & chemical reagents. The molecular structures of detected ingredients would be identified within one analytical instrument, and can be verified by other platforms; The corresponding concentrations of verified chemicals in complicated chemical reagents would be determined by quantitative analysis. Based on the description of the fine chemicals from our clients, the technical support can issue & develop the optimal analytical proposal. Generally, the typical analytic proposal would be performed as shown in Figure 1.

 Composition Analysis

Figure 1. Chemical Composition Analysis

  • Sample Fractionation: the chemical samples would be analyzed with Fourier Transform infrared spectroscopy (FT IR) & Nuclear Magnetic Resonance spectroscopy (NMR), and the components would be explored, estimated & sorted;
  • Fraction Analysis: the consequent analytic protocols would be prepared for different fractions;
  • Compound Profiling: the information from different fractions would be combined & validated, and experimental spectra would be isolated for comparison with standard spectra in database, such as chemical structural database (including 2,200,000 compounds), and UV spectra database(including 150,000 compounds) and MS spectra database (including 12,000 compounds);
  • Component Quantification: the accurate compositions of identified ingredients would be determined if required.

Chemical Composition Analysis at Creative Proteomics

In order to get reliable chemical composition analysis, it usually needs a series of analytical instruments & devices for ingredient profiling and accurate quantification. The analytical laboratory of Creative Proteomics has established integrated analytical facilities including the following analytical techniques:

  • Spectroscopy (UV, IR, NMR)
  • Chromatography (LC, GC, IC)
  • Mass Spectrometry (MS, MS/MS, GC-MS & LC-MS)
  • Fluorescence Spectrometer
  • Elemental Analyzer
  • Energy Dispersive Spectroscopy

Flexible combination of various analytic instruments can be achieved for consequent work based on the analytical results of the last step, during the entire analytical procedure. Our experienced tech staff and technicians are glad to discuss the inquiry with you, and provide the optimal procedure for your case at a cost-effective rate. Based on professional technology platforms, Creative Proteomics can provide various composition analysis services to assist with your scientific research, including:

At Creative Proteomics, we have the state-of-the-art instrumentation for chemical composition analysis. If you have any questions or specific needs, do not hesitate to contact us.

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