Creative Proteomics presents a comprehensive array of state-of-the-art services for the physicochemical characterization of DNA and RNA drugs, demonstrating our unwavering commitment to advancing the field of DNA and RNA therapeutics. Our cadre of seasoned scientists and cutting-edge facilities guarantee precise and dependable characterization, instilling confidence in your research and drug development endeavors.

Introduction of DNA & RNA Drug Physicochemical Characterization

Physicochemical characterization of DNA and RNA drugs encompasses a spectrum of analytical techniques and assessments specifically tailored to appraise the physical and chemical attributes of these therapeutic nucleic acids. This characterization entails the determination of crucial parameters such as molecular weight, spin, molar extinction coefficient, and other properties that exert influence on the performance and safety of the drug. Insights derived from physicochemical characterization data are invaluable in the development of DNA and RNA drugs, ensuring alignment with regulatory standards and guidelines.

Our DNA & RNA Drug Physicochemical Characterization Services

Creative Proteomics extends a comprehensive suite of physicochemical characterization services for DNA & RNA drugs. Our cutting-edge facilities and adept team ensure the delivery of precise and reliable results. Below are some of the key services we offer.

Molecular Weight Confirmation

Ensure the identity and structural integrity of your DNA & RNA drug with our advanced Mass Spectrometry (MS) techniques. Our molecular weight confirmation service provides precise determination of the exact molecular weight, verifying the sequence and detecting any impurities that could impact drug performance.

Optical Rotation Testing Service

Accurately assess the purity of chiral DNA & RNA compounds using our optical rotation testing service. We employ state-of-the-art instruments to determine the specific rotation, identifying enantiomeric impurities that may affect the drug's quality and pharmacological properties.

pH Testing Service

Gain insights into your DNA & RNA drug's behavior under different pH conditions with our pH testing service. Measuring solubility, stability, and interactions at various pH values aids in formulation development and identifies potential pH-dependent issues.

pK_a Determination Service

Understand the behavior of your DNA & RNA drug under varying pH conditions with our pK_a determination service. Our skilled scientists utilize titration and spectroscopic techniques to accurately determine pK_a values, aiding in formulation development and optimizing drug stability.

Moisture Content Determination Service

Ensure the stability and quality of your DNA & RNA drug with our moisture content determination service. Excessive moisture can lead to degradation, compromising drug performance. Our Karl Fischer titration and gravimetric analysis deliver precise measurements for meeting specified moisture specifications.

Molar Extinction Coefficient Determination

Quantify drug concentration accurately with our molar extinction coefficient determination service. Our spectroscopic methods, including UV absorption spectroscopy, enable precise measurement of ε values, critical for formulation and in vivo studies.

Melting Temperature (Tm) Testing Service

Assess the thermal stability of your DNA & RNA drug with our Tm testing service. The melting temperature is crucial for understanding drug stability and interactions. Our Differential Scanning Calorimetry (DSC) and UV melting analysis deliver reliable Tm values for effective drug delivery system design.

Size and Aggregation Analysis

Creative Proteomics offers professional DNA & RNA drug size and aggregation analysis services. We employ state-of-the-art equipment and techniques to provide comprehensive insights into DNA & RNA drug behavior.

Why Choose Us?

Expertise

Our team of skilled scientists possesses vast experience in the field of DNA & RNA drug physicochemical characterization.

State-of-the-Art Facilities

Creative Proteomics is equipped with advanced instrumentation, ensuring high-quality data and timely execution of projects.

Customizable Solutions

We understand that each project is unique, and we offer flexible and customizable service packages to meet your specific requirements.

Regulatory Compliance

Our services adhere to stringent regulatory guidelines, ensuring your data is submission-ready for approval processes.

Confidentiality

We prioritize the confidentiality of your projects and ensure secure data transfer and storage.

Customer Support

Our dedicated customer support team is available to assist you throughout the project and answer any queries you may have.

Explore the potential of your DNA & RNA drug candidates with Creative Proteomics' physicochemical characterization services. Contact us today to discuss your project's specific needs, and let us be your partner in achieving success in DNA & RNA drug development.