Creative Proteomics is committed to advancing the field of DNA & RNA drug carrier characterization. Understanding the complexities of drug carriers is critical for optimizing drug delivery strategies, and Creative Proteomics is at the forefront of providing cutting-edge solutions in this area.
Nucleic acid-based drug delivery systems encompass the analysis of carriers utilized for delivering therapeutic substances to targeted locations within the body. These carriers may comprise viral vectors, liposomes, and other nanoscale platforms designed to efficiently transport therapeutic agents like nucleic acids or small molecules to specific cells or tissues. The characterization process involves a comprehensive evaluation of various parameters, such as carrier composition, encapsulation efficiency, size distribution, surface charge, stability, and payload release kinetics. By comprehending these crucial factors, researchers and pharmaceutical entities can optimize drug delivery approaches to bolster effectiveness while mitigating potential undesired repercussions.
Fig. 1. For lipid nanoparticles, a lipid with a positive charge is used as the building block. (Shin H., et al., 2018)
Creative Proteomics offers a comprehensive range of services that cover all aspects of DNA & RNA drug carrier characterization. We offer, but are not limited to, the following services.
Capsid Protein Composition Analysis
We offer specialized capsid protein composition analysis services. Our advanced analytical techniques allow us to accurately identify and quantify capsid proteins to understand their composition and assembly, which provides invaluable information for understanding vector structure. This facilitates subsequent optimization of drug delivery systems.
Encapsulation Efficiency (VLP) Determination
We offer specialized testing services for encapsulation efficiency of therapeutic cargo in virus-like particles (VLPs). VLPs have received a lot of attention as drug carriers, and determining encapsulation efficiency can help researchers optimize VLP-based drug delivery systems.
Encapsulation Efficiency (LNP) Determination
We offer specialized encapsulation efficiency testing services for lipid nanoparticles (LNPs), which are multifunctional carriers that hold great promise for nucleic acid delivery. Our characterization services determine the encapsulation efficiency of LNPs to optimize nucleic acid delivery systems.
We offer lipid nanoparticle composition analysis services, which, through detailed analysis and characterization, can provide our clients with valuable information about lipid ratios and potential interactions with therapeutic drugs.
Our DNA & RNA drug carrier characterization services follow a systematic workflow to ensure accurate and comprehensive analysis.
Sample Preparation
Clients provide us with drug carrier samples, which may include viral vectors, liposomes, or other nano-scale systems.
Analytical Techniques
We employ a combination of cutting-edge analytical techniques, including mass spectrometry, chromatography, and spectroscopy, to analyze the samples thoroughly.
Data Analysis
Our team of experts interprets the data obtained from the analysis to derive meaningful conclusions about the drug carriers' characteristics.
Report Generation
A comprehensive report is generated, including detailed results and interpretations. Clients can also consult with our scientists for further insights and discussions.
Our DNA & RNA drug carrier characterization services find applications in various fields. There are some key applications.
Creative Proteomics is committed to pushing the boundaries of DNA & RNA drug carrier characterization, providing researchers and pharmaceutical companies with the insights needed to revolutionize drug delivery strategies. With our comprehensive services and advanced analytical techniques, we aim to facilitate the development of novel therapeutics that are safer, more efficient, and more targeted. Contact us today to discuss your project.
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