Stable isotope labeling by amino acids in cell culture (SILAC), a type of the metabolic labeling experiment, can label an entire proteome with heavy isotopes in vivo for quantitative proteomics. In these experiments, the labeled and unlabeled samples are mixed before sample preparation, which can prevent variability from distorting the quantification results. So far, rodents (like mice) can be fully labeled with SILAC amino acids. The heavy tissues are used as internal standards for quantitative proteomic analysis. Compared to feeding a mouse for a period of time, using prelabeled SILAC mouse tissue as quantitative standards will save a lot of time, effort, and money.
As a supplier of isotope labeled products in the industry, Creative Proteomics offers more than 10,000 products labeled with different isotopes of carbon, hydrogen, nitrogen, and oxygen. Creative Proteomics supplies SILAC mouse tissue both male and female, including abdominal adipose tissue, bladder, brain tissue, breast tissue, cecum tissue, colon tissue, eye tissue, and so on. Custom synthesis is also available to meet our customers’ research needs.
