SILAC Mouse Feed


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Cat# Product Name Price
CPIL105246MouseExpress (15N, 98%) MOUSE FEED IRRADIATED PREPARED WITH SPIRULINA (U-15N, 98%+)INQUIRY
CPIL105245MouseExpress (15N, 98%) MOUSE FEED KIT IRRADIATED PREPARED WITH SPIRULINAINQUIRY
CPIL105249MouseExpress (15N, 98%) MOUSE FEED KIT PREPARED WITH SPIRULINAINQUIRY
CPIL105250MouseExpress (15N, 98%) MOUSE FEED PREPARED WITH SPIRULINA (U-15N, 98%+)INQUIRY
CPIL105254MouseExpress L-LEUCINE (5,5,5-D3, 99%) IRRADIATED MOUSE FEEDINQUIRY
CPIL105258MouseExpress L-LEUCINE (5,5,5-D3, 99%) MOUSE FEEDINQUIRY
CPIL105257MouseExpress L-LEUCINE (5,5,5-D3, 99%) MOUSE FEED KITINQUIRY
CPIL105253MouseExpress L-LEUCINE (5,5,5-D3, 99%) MOUSE FEED KIT IRRADIATEDINQUIRY
CPIL105256MouseExpress L-LYSINE (13C6, 99%) IRRADIATED MOUSE FEEDINQUIRY
CPIL105260MouseExpress L-LYSINE (13C6, 99%) MOUSE FEEDINQUIRY
CPIL105259MouseExpress L-LYSINE (13C6, 99%) MOUSE FEED KITINQUIRY
CPIL105251MouseExpress UNLABELED MOUSE FEED PREPARED WITH UNLABELED SPIRULINAINQUIRY

Stable isotope labeling by amino acids in cell culture (SILAC) is a popular and mass spectrometry-based technique for quantitative proteomics. SILAC mouse is a novel in vivo proteomics approach that allows the quantitative determination of protein patterns of mouse tissues. The principle of SILAC mouse is similar to that of SILAC approach aiming at the quantification of proteins in cell cultures. The mouse is almost labeled by feeding the heavy diet. SILAC mouse has various applications. The SILAC mouse can serve as a reference model at any biological scale, including single proteins of interest and the whole organ. In addition, some cell types like intestinal epithelium that are difficult to analysis ex vivo can be studied by the in vivo SILAC mouse.

SILAC Mouse FeedFigure 1. Mice are SILAC labeled by being fed a pelleted, lysine-free diet supplemented with normal or heavy lysine. (Krüger M, et al., 2008)

As a supplier of isotope labeled products in the industry, Creative Proteomics offers more than 10,000 products labeled with different isotopes of carbon, hydrogen, nitrogen, and oxygen. Creative Proteomics supplies SILAC mouse feed, including Mouse Express® unlabeled mouse feed, MouseExpress® L-leucine mouse feed kit, MouseExpress® L-lysine mouse feed kit, spirulina mouse feed, and so on. Custom synthesis is also available to meet our customers’ research needs.

Reference:

1.Krüger M, et al. SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. Cell, 2008, 134(2): 353-364.

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