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ROBO1 Full-Length MS Protein Standard

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Product Description


NameROBO1 Full-Length MS Protein Standard
Cat#CPFL327713
Protein Nameroundabout, axon guidance receptor, homolog 1 (Drosophila)
SymbolROBO1
SynonymsDUTT1; FLJ21882; MGC131599; MGC133277; SAX3; FLJ21882; MGC131599; MGC133277; SAX3; axon guidance receptor; roundabout 1; roundabout, axon guidance receptor, homolog 1 (Drosophila)
AccessionNM_001145844
Cytogenetic3p12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionROBO1 Full-Length MS Protein Standard (NP_001139316), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.

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