RASGRP3 Full-Length MS Protein Standard


Product Description:

Name RASGRP3 Full-Length MS Protein Standard
Cat# CPFL327703
Protein NameRAS guanyl releasing protein 3 (calcium and DAG-regulated)
SymbolRASGRP3
SynonymsGRP3
AccessionNM_001139488
Cytogenetic2p25.1-p24.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW78.2 kDa
Expression TrueORF CloneRC227703
DescriptionRASGRP3 Full-Length MS Protein Standard (NP_001132960), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 )

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