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RNASEH2B Full-Length MS Protein Standard

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Product Description


NameRNASEH2B Full-Length MS Protein Standard
Cat#CPFL326833
Protein Nameribonuclease H2, subunit B
SymbolRNASEH2B
SynonymsAGS2; DLEU8
AccessionNM_001142279
Cytogenetic13q14.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionRNASEH2B Full-Length MS Protein Standard (NP_001135751), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

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