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NFATC4 Full-Length MS Protein Standard

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Product Description


NameNFATC4 Full-Length MS Protein Standard
Cat#CPFL326608
Protein Namenuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
SymbolNFATC4
SynonymsNF-AT3; NF-ATC4; NFAT3
AccessionNM_001136022
Cytogenetic14q11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNFATC4 Full-Length MS Protein Standard (NP_001129494), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.

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