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ROBO2 Full-Length MS Protein Standard

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Product Description


NameROBO2 Full-Length MS Protein Standard
Cat#CPFL326390
Protein Nameroundabout, axon guidance receptor, homolog 2 (Drosophila)
SymbolROBO2
SynonymsSAX3
AccessionNM_001128929
Cytogenetic3p12.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionROBO2 Full-Length MS Protein Standard (NP_001122401), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants.

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