ITGB2 Full-Length MS Protein Standard
Product Description:
| Name |
ITGB2 Full-Length MS Protein Standard |
| Cat# |
CPFL326157 |
| Protein Name | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| Symbol | ITGB2 |
| Synonyms | CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7 |
| Accession | NM_001127491 |
| Cytogenetic | 21q22.3 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Description | ITGB2 Full-Length MS Protein Standard (NP_001120963), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
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