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DNAJC2 Full-Length MS Protein Standard

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Product Description


NameDNAJC2 Full-Length MS Protein Standard
Cat#CPFL325965
Protein NameDnaJ (Hsp40) homolog, subfamily C, member 2
SymbolDNAJC2
SynonymsMPHOSPH11; MPP11; ZRF1; ZUO1
AccessionNM_001129887
Cytogenetic7q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDNAJC2 Full-Length MS Protein Standard (NP_001123359), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

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