MPP5 Full-Length MS Protein Standard


Product Description:

Name MPP5 Full-Length MS Protein Standard
Cat# CPFL324752
Protein Namemembrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
SymbolMPP5
SynonymsPALS1
AccessionNM_022474
Cytogenetic14q23.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW77.1 kDa
Expression TrueORF CloneRC224752
DescriptionMPP5 Full-Length MS Protein Standard (NP_071919), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene.

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