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NEFM Full-Length MS Protein Standard

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Product Description


NameNEFM Full-Length MS Protein Standard
Cat#CPFL324475
Protein Nameneurofilament, medium polypeptide
SymbolNEFM
SynonymsNEF3; NF-M; NFM
AccessionNM_005382
Cytogenetic8p21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNEFM Full-Length MS Protein Standard (NP_005373), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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