Home > Products > Stable Isotope Labeled Full Length MS Protein Standard > E2F5 Full-Length MS Protein Standard

E2F5 Full-Length MS Protein Standard

INQUIRY>

Product Description


NameE2F5 Full-Length MS Protein Standard
Cat#CPFL324285
Protein NameE2F transcription factor 5, p130-binding
SymbolE2F5
SynonymsE2F-5
AccessionNM_001951
Cytogenetic8q21.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionE2F5 Full-Length MS Protein Standard (NP_001942), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.

Products List:

Cat#Protein SequencePrice

If the product of interest is not available in our catalog, we can synthesize for you with our quality controlled
Customized Synthesized Peptide/Proteins Service!

Online Inquiry


Please input "proteomics" as verification code.