UNC5C Full-Length MS Protein Standard


Product Description:

Name UNC5C Full-Length MS Protein Standard
Cat# CPFL324257
Protein Nameunc-5 homolog C (C. elegans)
SymbolUNC5C
SynonymsUNC5H3
AccessionNM_003728
Cytogenetic4q21-q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW102.9 kDa
Expression TrueORF CloneRC224257
DescriptionUNC5C Full-Length MS Protein Standard (NP_003719), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.

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