CALD1 Full-Length MS Protein Standard


Product Description:

Name CALD1 Full-Length MS Protein Standard
Cat# CPFL323989
Protein Namecaldesmon 1
SymbolCALD1
SynonymsCDM; H-CAD; HCAD; L-CAD; LCAD; NAG22
AccessionNM_033157
Cytogenetic7q33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW65.4 kDa
Expression TrueORF CloneRC223989
DescriptionCALD1 Full-Length MS Protein Standard (NP_149347), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

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