SCN4B Full-Length MS Protein Standard


Product Description:

Name SCN4B Full-Length MS Protein Standard
Cat# CPFL323951
Protein Namesodium channel, voltage-gated, type IV, beta subunit
SymbolSCN4B
SynonymsATFB17; LQT10; Navbeta4
AccessionNM_174934
Cytogenetic11q23.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW22 kDa
Expression TrueORF CloneRC223951
DescriptionSCN4B Full-Length MS Protein Standard (NP_777594), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.

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