DHX36 Full-Length MS Protein Standard


Product Description:

Name DHX36 Full-Length MS Protein Standard
Cat# CPFL323929
Protein NameDEAH (Asp-Glu-Ala-His) box polypeptide 36
SymbolDHX36
SynonymsDDX36; G4R1; MLEL1; RHAU
AccessionNM_020865
Cytogenetic3q25.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW114.6 kDa
Expression TrueORF CloneRC223929
DescriptionDHX36 Full-Length MS Protein Standard (NP_065916), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.

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