RUNX1 Full-Length MS Protein Standard


Product Description:

Name RUNX1 Full-Length MS Protein Standard
Cat# CPFL323854
Protein Namerunt-related transcription factor 1
SymbolRUNX1
SynonymsAML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB
AccessionNM_001001890
Cytogenetic21q22.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW48.6 kDa
Expression TrueORF CloneRC223854
DescriptionRUNX1 Full-Length MS Protein Standard (NP_001001890), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

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