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RASGRF2 Full-Length MS Protein Standard


Product Description

NameRASGRF2 Full-Length MS Protein Standard
Protein NameRAS protein-specific guanine nucleotide-releasing factor 2
SynonymsGRF2; RAS-GRF2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW140.6 kDa
Expression TrueORF CloneRC223580
DescriptionRASGRF2 Full-Length MS Protein Standard (NP_008840), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways.

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