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EIF2B3 Full-Length MS Protein Standard

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Product Description


NameEIF2B3 Full-Length MS Protein Standard
Cat#CPFL323570
Protein Nameeukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
SymbolEIF2B3
SynonymsEIF-2B; EIF2Bgamma
AccessionNM_020365
Cytogenetic1p34.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionEIF2B3 Full-Length MS Protein Standard (NP_065098), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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