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BCAS1 Full-Length MS Protein Standard

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Product Description


NameBCAS1 Full-Length MS Protein Standard
Cat#CPFL323329
Protein Namebreast carcinoma amplified sequence 1
SymbolBCAS1
SynonymsAIBC1; NABC1
AccessionNM_003657
Cytogenetic20q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionBCAS1 Full-Length MS Protein Standard (NP_003648), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene.

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