| Name | ERCC4 Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL323300 |
| Protein Name | excision repair cross-complementing rodent repair deficiency, complementation group 4 |
| Symbol | ERCC4 |
| Synonyms | ERCC11; FANCQ; RAD1; XPF |
| Accession | NM_005236 |
| Cytogenetic | 16p13.12 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 104.3 kDa |
| Expression TrueORF Clone | RC223300 |
| Description | ERCC4 Full-Length MS Protein Standard (NP_005227), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5 incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). |
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