ABCE1 Full-Length MS Protein Standard


Product Description:

Name ABCE1 Full-Length MS Protein Standard
Cat# CPFL323295
Protein NameATP-binding cassette, sub-family E (OABP), member 1
SymbolABCE1
SynonymsABC38; OABP; RLI; RNASEL1; RNASELI; RNS4I
AccessionNM_002940
Cytogenetic4q31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW67.1 kDa
Expression TrueORF CloneRC223295
DescriptionABCE1 Full-Length MS Protein Standard (NP_002931), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

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